The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways
- Author
- MARTIN, Carol B1 ; MAHON, Gwendolyn M2 ; KLINGER, Mark B3 ; KAY, Robert J3 ; SYMONS, Marc4 ; DER, Channing J1 ; WHITEHEAD, Ian P2
[1] Department of Pharmacology and Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina NC 27599-7295, United States
[2] Department of Microbiology and Molecular Genetics, UMDNJ-New Jersey Medical School, Newark, New Jersey, NJ 07103-2714, United States
[3] Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver. British Columbia, V5Z-4E6, Canada
[4] Laboratory of Molecular Oncology, Picower Institute of Medical Research Manhasset, New York, NY 11030, United States - Source
Oncogene (Basingstoke). 2001, Vol 20, Num 16, pp 1953-1963 ; ref : 1 p.1/4
- ISSN
- 0950-9232
- Scientific domain
- Cell biology, histology; Medical oncology; Genetics
- Publisher
- Nature Publishing, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Fibroblaste Gène onc cellulaire Protéine G Récepteur biologique Souris Thrombine Transduction signal Transformation cellulaire Lignée NIH3T3 Protéine PAR1 Protéine Rho Lignée cellulaire Mammalia Rodentia Vertebrata
- Keyword (en)
- Fibroblast C-Onc gene G protein Biological receptor Mouse Thrombin(drug) Signal transduction Cell transformation Cell line Mammalia Rodentia Vertebrata
- Keyword (es)
- Fibroblasto Gen onc celular Proteína G Receptor biológico Ratón Trombina Transducción señal Transformación celular Línea celular Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes
- Discipline
- Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1091121
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.onc.1204281 
https://dx.doi.org/10.1038/sj.onc.1204281
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