Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors
- Author
- DRAGOVICH, P. S1 ; RU ZHOU1 ; MEADOR, J. W1 ; PATICK, A. K1 ; FORD, C. E1 ; BROTHERS, M. A1 ; BINFORD, S. L1 ; MATTHEWS, D. A1 ; FERRE, R. A1 ; WORLAND, S. T1 ; WEBBER, S. E1 ; PRINS, T. J1 ; KWOK, A. K1 ; OKANO, K1 ; FUHRMAN, S. A1 ; ZALMAN, L. S1 ; MALDONADO, F. C1 ; BROWN, E. L1
[1] Agouron Pharmaceuticals, Inc., 3565 General Atomics Court, San Diego, CA 92121, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2000, Vol 10, Num 1, pp 45-48
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antiviral Benzothiazole dérivé Carboxamide Dipeptide Hétérocycle azote Hétérocycle soufre azote In vitro Inhibiteur enzyme Lactame Peptide Picornain 3C Relation structure activité Rhinovirus humain Synthèse chimique Synthèse peptidique Phénylalanine dérivé Pyrrolidin-2-one dérivé Valine dérivé Cysteine endopeptidases Enzyme Hydrolases Peptidases Picornaviridae Rhinovirus Virus
- Keyword (en)
- Antiviral Benzothiazole derivatives Carboxamide Dipeptides Nitrogen heterocycle Sulfur nitrogen heterocycle In vitro Enzyme inhibitor Lactam Peptides Picornain 3C Structure activity relation Human rhinovirus Chemical synthesis Peptide synthesis Cysteine endopeptidases Enzyme Hydrolases Peptidases Picornaviridae Rhinovirus Virus
- Keyword (es)
- Antiviral Benzotiazol derivado Carboxamida Dipéptido Heterociclo nitrógeno Heterociclo azufre nitrógeno In vitro Inhibidor enzima Lactamo Péptido Picornain 3C Relación estructura actividad Human rhinovirus Síntesis química Síntesis peptídica Cysteine endopeptidases Enzima Hydrolases Peptidases Picornaviridae Rhinovirus Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S05 Antiviral agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1243364
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0960-894X(99)00587-9 
https://dx.doi.org/10.1016/S0960-894X(99)00587-9
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