Modulation of benzo[a]pyrene diolepoxide-DNA adduct levels in human white blood cells by CYP1A1, GSTM1 and GSTT1 polymorphism
- Author
- ROJAS, M1 ; CASCORBI, I2 ; ALEXANDROV, K1 ; KRIEK, E3 ; AUBURTIN, G4 ; MAYER, L4 ; KOPP-SCHNEIDER, A5 ; ROOTS, I2 ; BARTSCH, H1
[1] Division of Toxicology and Cancer Risk Factors, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
[2] Institute of Clinical Pharmacology, University Clinic Charité, Humboldt University of Berlin, Schumannstrasse 20/21, 10098 Berlin, Germany
[3] Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, Netherlands
[4] Institut National de l'Environnement Industriel et des Risques, 60550 Verneuil en Hallate, France
[5] Division of Biostatistics, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany - Source
Carcinogenesis (New York. Print). 2000, Vol 21, Num 1, pp 35-41 ; ref : 52 ref
- CODEN
- CRNGDP
- ISSN
- 0143-3334
- Scientific domain
- Medical oncology; Genetics; Pharmacology drugs; Toxicology
- Publisher
- Oxford University Press, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Adduit moléculaire Benzo[a]pyrène-7,8-diol(9,10-époxy-7,8,9,10-tétrahydro) Bronchopulmonaire Carcinogenèse Composé aromatique polycyclique DNA Exposition professionnelle Fonderie Four coke Fumeur Génotype Génétique Homme Industrie métallurgique Leucocyte Médecine travail Non fumeur Polymorphisme Risque élevé Toxicité Tumeur maligne Cytochrome CYP1A1 Gene GSTM1 Appareil respiratoire pathologie Bronche pathologie Poumon pathologie
- Keyword (en)
- Molecular adduct Bronchopulmonary Carcinogenesis Polycyclic aromatic compound DNA Occupational exposure Foundry Coke oven Smoker Genotype Genetics Human Metallurgical industry Leukocyte Occupational medicine Non smoker Polymorphism High risk Toxicity Malignant tumor Respiratory disease Bronchus disease Lung disease
- Keyword (es)
- Producto adición molecular Broncopulmonar Carcinogénesis Compuesto aromático policíclico DNA Exposición profesional Fundería Horno coque Fumador Genotipo Genética Hombre Industria metalúrgica Leucocito Medicina ocupacional No fumador Polimorfismo Riesgo alto Toxicidad Tumor maligno Aparato respiratorio patología Bronquio patología Pulmón patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03L Chemical and industrial products toxicology. Toxic occupational diseases / 002B03L06 Various organic compounds
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- Pulmonology Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1328299
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1093/carcin/21.1.35 
https://dx.doi.org/10.1093/carcin/21.1.35
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