Opposite effects of substance P fragments C (anxiogenic) and N (anxiolytic) injected into dorsal periaqueductal gray
- Author
- DE ARAUJO, Joao E1 ; HUSTON, Joseph P2 ; BRANDAO, Marcus L1
[1] Laboratório de Psicobiologia, FFCLRP, Campus USP, Av., Bandeirantes 3900, 14049-901 Ribeirão Preto, SP, Brazil
[2] Institute of Physiological Psychology and Center for Biological and Medical Research, University of Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany - Source
European journal of pharmacology. 2001, Vol 432, Num 1, pp 43-51 ; ref : 1 p.1/4
- CODEN
- EJPHAZ
- ISSN
- 0014-2999
- Scientific domain
- Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Angoisse anxiété Animal Antagoniste Encéphale Mécanisme action Pathogénie Physiopathologie Psychotrope Rat Relation structure activité Récepteur tachykinine NK1 Substance P Substance grise périaqueducale Système nerveux central Séquence C terminale Séquence N terminale Séquence aminoacide Tranquillisant Voie intracérébrale Voie intrapéritonéale WIN 51 708 Hormone peptide Mammalia Neuropeptide Rodentia Vertebrata
- Keyword (en)
- Biological activity Anxiety Animal Antagonist Brain (vertebrata) Mechanism of action Pathogenesis Pathophysiology Psychotropic Rat Structure activity relation NK1 Tachykinin receptor Substance P Periaqueductal gray matter Central nervous system C terminal-Sequence N terminal-Sequence Aminoacid sequence Tranquillizer Intracerebral administration Intraperitoneal administration Peptide hormone Mammalia Neuropeptide Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Angustia ansiedad Animal Antagonista Encéfalo Mecanismo acción Patogenia Fisiopatología Psicotropo Rata Relación estructura actividad Receptor taquikinina NK1 Substancia P Substancia gris periacueductal Sistema nervioso central Secuencia C terminal Secuencia N terminal Secuencia aminoácido Tranquilizante Vía intracerebral Vía intraperitoneal Hormona péptido Mammalia Neuropéptido Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B03 Psycholeptics: tranquillizer, neuroleptic.
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18C Adult and adolescent clinical studies / 002B18C08 Anxiety disorders. Neuroses / 002B18C08E Miscellaneous
- Discipline
- Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 13378009
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0014-2999(01)01460-1 
https://dx.doi.org/10.1016/S0014-2999(01)01460-1
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