Quantification of nimesulide in human plasma by high-performance liquid chromatography/tandem mass spectrometry. Application to bioequivalence studies
- Author
- BARRIENTOS-ASTIGARRAGA, Rafael Eliseo1 ; BORGES VANNUCHI, Yuri1 ; SUCUPIRA, Mauro1 ; AGNALDO MORENO, Ronilson1 ; MUSCARA, Marcelo Nicolas1 ; DE NUCCI, Gilberto1
[1] Cartesius Analytical Unit, Department of Pharmacology, Institute of Biomedical Sciences, Av. Prof. Lineu Prestes 1524, Sao Paulo, SP, 05508-900, Brazil - Source
Journal of mass spectrometry. 2001, Vol 36, Num 12, pp 1281-1286 ; ref : 9 ref
- ISSN
- 1076-5174
- Scientific domain
- Biochemistry, molecular biology, biophysics; Analytical chemistry; Organic chemistry
- Publisher
- Wiley, Chichester
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Analgésique Analyse chimique Analyse quantitative Antiinflammatoire non stéroïde Antipyrétique Biodisponibilité Bioéquivalence Chromatographie HPLC Composé benzénique Composé nitro Homme Inhibiteur enzyme Liquide biologique Méthode couplée Nimésulide Pharmacocinétique Plasma sanguin Prostaglandin-endoperoxide synthase Sang Spectrométrie masse tandem Sulfonamide Voie orale Enzyme Oxidoreductases
- Keyword (en)
- Analgesic Chemical analysis Quantitative analysis Non steroidal antiinflammatory agent Antipyretic Bioavailability Bioequivalence HPLC chromatography Benzenic compound Nitro compound Human Enzyme inhibitor Biological fluid Coupled method Nimesulide Pharmacokinetics Blood plasma Prostaglandin-endoperoxide synthase Blood Mass spectrometry MS/MS Sulfonamide Oral administration Enzyme Oxidoreductases
- Keyword (es)
- Analgésico Análisis químico Análisis cuantitativo Antiinflamatorio no esteroide Antipirético Biodisponibilidad Bioequivalencia Cromatografía HPLC Compuesto bencénico Compuesto nitro Hombre Inhibidor enzima Líquido biológico Método acoplado Nimesulida Farmacocinética Plasma sanguíneo Prostaglandin-endoperoxide synthase Sangre Espectrometría masa en tandem Sulfonamida Vía oral Enzima Oxidoreductases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 13390953
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/jms.232 
https://dx.doi.org/10.1002/jms.232
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