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Effects of polyethylene glycol attachment on physicochemical and biological stability of E. coli L-asparaginase

Author
LEARTH SOARES, Alexandre1 ; MANSO GUIMARAES, Gledson1 ; POLAKIEWICZ, Bronislaw1 ; NOGUEIRA DE MORAES PITOMBO, Ronaldo1 ; ABRAHAO-NETO, José1
[1] Department of Biochemical and Pharmaceutical Technology, School of Pharmaceutical Sciences, Av. Prof. Lineu Prestes, 580, Bloco 16, University of São Paulo, P.O. Box 66083, CEP 05315-970, Sao Paulo, SP, Brazil
Source

International journal of pharmaceutics. 2002, Vol 237, Num 1-2, pp 163-170 ; ref : 28 ref

CODEN
IJPHDE
ISSN
0378-5173
Scientific domain
Pharmacology drugs
Publisher
Elsevier, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Keyword (fr)
Activité catalytique Asparaginase Composé conjugué Escherichia coli Ethylène oxyde polymère Homme In vitro Leucémie Lyophilisation Stabilité Sérum Technologie pharmaceutique Bactérie Enterobacteriaceae Enzyme Hydrolases Hémopathie maligne
Keyword (en)
Catalyst activity Asparaginase Conjugated compound Escherichia coli Ethylene oxide polymer Human In vitro Leukemia Freeze drying Stability Serum Pharmaceutical technology Bacteria Enterobacteriaceae Enzyme Hydrolases Malignant hemopathy
Keyword (es)
Actividad catalítica Asparaginase Compuesto conjugado Escherichia coli Etileno óxido polímero Hombre In vitro Leucemia Liofilización Estabilidad Suero Tecnología farmacéutica Bacteria Enterobacteriaceae Enzima Hydrolases Hemopatía maligna
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A01 Physicochemical properties. Structure-activity relationships

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
13613090

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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