Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
- Author
- SUZUKI, Nobutaka1 ; SUZUKI, Shinobu1 ; PENNINGER, Josef M1 ; WESCHE, Holger3 ; OHASHI, Pamela S2 ; MAK, Tak W1 ; YEH, Wen-Chen1 ; DUNCAN, Gordon S1 ; MILLAR, Douglas G2 ; WADA, Teiji1 ; MIRTSOS, Christine1 ; TAKADA, Hidetoshi1 ; WAKEHAM, Andrew1 ; ITIE, Annick1 ; SHYUN LI3
[1] Amgen Institute, Ontario Cancer Institute and Department of Medical Biophysics, University of Toronto, 620 University Avenue, Suite 706, Toronto, Ontario M5G 2C1, Canada
[2] Departments of Medical Biophysics and Immunology, University of Toronto, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada
[3] Tularik Incorporation, 2 Corporate Drive, South San Francisco, California 94080, United States - Source
Nature (London). 2002, Vol 416, Num 6882, pp 750-754 ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- French
- Keyword (fr)
- Immunité naturelle Interleukine 1 Relation hôte agent Relation hôte virus Souris Récepteur type Toll Cytokine Mammalia Rodentia Vertebrata
- Keyword (en)
- Natural immunity Interleukin 1 Host agent relation Host virus relation Mouse Cytokine Mammalia Rodentia Vertebrata
- Keyword (es)
- Inmunidad natural Interleuquina 1 Relación huesped agente Relación huesped virus Ratón Citoquina Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A06 Fundamental immunology / 002A06C Immunobiology / 002A06C05 Analysis of the immune response. Humoral and cellular immunity / 002A06C05D Regulatory factors and their cellular receptors / 002A06C05D1 Lymphokines, interleukins ( function, expression)
- Discipline
- Fundamental immunology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 13616893
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature736 
https://dx.doi.org/10.1038/nature736
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