Dopamine D2 and D3 receptor occupancy in normal humans treated with the antipsychotic drug aripiprazole (OPC 14597): A study using positron emission tomography and [11c]raclopride
- Author
- YOKOI, Fuji; GRÜNDER, Gerhard; BIZIERE, Kathleen; STEPHANE, Massoud; DOGAN, Ahmet S; DANNALS, Robert F; RAVERT, Hayden; SURI, Ajit; BRAMER, Steven; WONG, Dean F
Departments of Radiology (Division of Nuclear Medicine), Psychiatry, and Environmental Health Sciences (Division of Radiation Health Sciences), Johns Hopkins Medical Institutions, Baltimore, MD, United States
Otsuka America Pharmaceutical, Inc., Rockville, MD, United States - Source
Neuropsychopharmacology (New York, NY). 2002, Vol 27, Num 2, pp 248-259 ; ref : 2 p.1/4
- CODEN
- NEROEW
- ISSN
- 0893-133X
- Scientific domain
- Neurology; Pharmacology drugs; Psychology, psychopathology, psychiatry
- Publisher
- Nature Publishing, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Aripiprazole Autorécepteur Encéphale Etat équilibre Homme Individu sain Interaction moléculaire Long terme Mécanisme action Neuroleptique Pharmacocinétique Plasma sanguin Psychotrope Récepteur dopaminergique D2 Récepteur dopaminergique D3 Sang Système nerveux central Voie orale OPC 14597
- Keyword (en)
- Aripiprazole Autoreceptor Brain (vertebrata) Equilibrium state Human Healthy subject Molecular interaction Long term Mechanism of action Neuroleptic Pharmacokinetics Blood plasma Psychotropic D2 Dopamine receptor D3 Dopamine receptor Blood Central nervous system Oral administration
- Keyword (es)
- Aripiprazol Autoreceptor Encéfalo Estado equilibrio Hombre Individuo sano Interacción molecular Largo plazo Mecanismo acción Neuroléptico Farmacocinética Plasma sanguíneo Psicotropo Receptor dopaminérgico D2 Receptor dopaminérgico D3 Sangre Sistema nervioso central Vía oral
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B03 Psycholeptics: tranquillizer, neuroleptic.
- Discipline
- Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 13742774
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0893-133X(02)00304-4 
https://dx.doi.org/10.1016/S0893-133X(02)00304-4
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