Staurosporine-induced G1 arrest in cancer cells depends on an intact pRB but is independent of p16 status
- Author
- WEIBO ZHOU1 ; YUAN LIN1 ; WERSTO, Robert2 ; CHREST, Joseph2 ; GABRIELSON, Edward1
[1] Department of Pathology, Johns Hopkins University School of Medicine, 418 No. Bond Street, Baltimore, MD 21231, United States
[2] Gerontology Research Center of the National Institute of Aging, 5600 Nathan Shock Drive, Baltimore, MD 21224, United States - Source
Cancer letters. 2002, Vol 183, Num 1, pp 103-107 ; ref : 26 ref
- CODEN
- CALEDQ
- ISSN
- 0304-3835
- Scientific domain
- Medical oncology
- Publisher
- Elsevier, Shannon
- Publication country
- Ireland
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Anticancéreux Cellule tumorale Cycle cellulaire Gène CDKN2 Gène suppresseur tumeur Homme In vitro Inhibiteur enzyme Lignée cellulaire établie Mécanisme action Phase G1 Protein kinase Protéine rétinoblastome Transduction signal Tumeur maligne Cyclin dependent kinase Gène p16 Staurosporine UCN 01 Enzyme Transferases
- Keyword (en)
- Biological activity Antineoplastic agent Tumor cell Cell cycle CDKN2 gene Tumor suppressor gene Human In vitro Enzyme inhibitor Established cell line Mechanism of action G1 Phase Protein kinase Retinoblastoma protein Signal transduction Malignant tumor Enzyme Transferases
- Keyword (es)
- Actividad biológica Anticanceroso Célula tumoral Ciclo celular Gen CDKN2 Gen supresor tumor Hombre In vitro Inhibidor enzima Línea celular establecida Mecanismo acción Fase G1 Protein kinase Proteína retinoblastoma Transducción señal Tumor maligno Enzima Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 13776037
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0304-3835(02)00101-5 
https://dx.doi.org/10.1016/S0304-3835(02)00101-5
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