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Accelerated resequestration of cytosolic calcium and suppression of the pro-inflammatory activities of human neutrophils by CGS 21680 in vitro

Author
ANDERSON, R1 ; VISSER, S. S2 ; RAMAFI, G1 ; THERON, A. J1
[1] Medical Research Council Unit for Inflammation and Immunity, Department of Immunology, Faculty of Medicine, University of Pretoria, South Africa
[2] Department of Internal Medicine, Division of Pulmonology, Faculty of Medicine, University of Pretoria, South Africa
Source

British journal of pharmacology. 2000, Vol 130, Num 4, pp 717-724 ; ref : 34 ref

CODEN
BJPCBM
ISSN
0007-1188
Scientific domain
Pharmacology drugs
Publisher
Nature Publishing, Basingstoke
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
AMP cyclique Activité biologique Agoniste Antagoniste Antiinflammatoire Calcium ion Homme In vitro Inflammation Leukocyte elastase Mécanisme action Neutrophile Oxydant Relation dose réponse Récepteur adénosinique A2 Système immunitaire CGS 21680 Récepteur adénosinique A2A Enzyme Hydrolases Peptidases Serine endopeptidases
Keyword (en)
Cyclic AMP Biological activity Agonist Antagonist Antiinflammatory agent Calcium ion Human In vitro Inflammation Leukocyte elastase Mechanism of action Neutrophil Oxidant Dose activity relation A2 Adenosine receptor Immune system Enzyme Hydrolases Peptidases Serine endopeptidases
Keyword (es)
AMP cíclico Actividad biológica Agonista Antagonista Antiinflamatorio Calcio ión Hombre In vitro Inflamación Leukocyte elastase Mecanismo acción Neutrófilo Oxidante Relación dosis respuesta Receptor adenosínico A2 Sistema inmunitario Enzima Hydrolases Peptidases Serine endopeptidases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09F Peptidergic system (neuropeptide, opioid peptide, opiates...). Adenosinergic and purinergic systems

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02L Bones, joints and connective tissue. Antiinflammatory agents

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
1412972

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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