A novel trivalent cation chelator Feralex dissociates binding of aluminum and iron associated with hyperphosphorylated τ of Alzheimer's disease
- Author
- SHIN, Ryong-Woon1 ; KRUCK, Theo P. A2 3 ; MURAYAMA, Harunobu4 ; KITAMOTO, Tetsuyuki1
[1] Department of Neurological Science, Tohoku University School of Medicine, 2-1 Seiryo-machi, Sendai 980-8575, Japan
[2] Department of Physiology, University of Toronto, Toronto, Ontario, M5S-1A1, Canada
[3] Neurogenetics Laboratory, Surrey Place Centre, 2 Surrey Place, Toronto, Ontario, M5 S-2C2, Canada
[4] Department of Pathology, Sendai City Hospital, Sendai 984-8501, Japan - Source
Brain research. 2003, Vol 961, Num 1, pp 139-146, 8 p ; ref : 30 ref
- CODEN
- BRREAP
- ISSN
- 0006-8993
- Scientific domain
- Neurology; Physiology, morphology
- Publisher
- Elsevier, Amsterdam
/
Elsevier, London
/
Elsevier, New York, NY
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Aluminum Alzheimer's disease Chelation Feralex-G and desferrioxamine Iron PHF T protein
- Keyword (fr)
- Aluminium Cation trivalent Chélation Démence Alzheimer Fer Phosphorylation Protéine tau Encéphale pathologie Maladie dégénérative Système nerveux central pathologie Système nerveux pathologie
- Keyword (en)
- Aluminium Trivalent cation Chelation Alzheimer disease Iron Phosphorylation Tau protein Cerebral disorder Degenerative disease Central nervous system disease Nervous system diseases
- Keyword (es)
- Aluminio Catión trivalente Quelación Demencia Alzheimer Hierro Fosforilación Proteína tau Encéfalo patología Enfermedad degenerativa Sistema nervosio central patología Sistema nervioso patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14469799
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0006-8993(02)03893-3 
https://dx.doi.org/10.1016/S0006-8993(02)03893-3
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