Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial

Author

VINCENT, Jean-Louis¹ ; ANGUS, Derek C² ; ARTIGAS, Antonio^{3 4} ; KALIL, Andre⁵ ; BASSON, Bruce R⁵ ; JAMAL, Hassan H⁵ ; JOHNSON, Gerald III⁵ ; BERNARD, Gordon R⁶
[1] Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Brussels, Belgium
[2] Department of Critical Care Medicine, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States
[3] Critical Care Center, Corporació Sanitaria Parc Tauli, Parc Tauli, Sabadell, Spain
[4] Cellular Biology and Physiology Department, Autonomous University of Barcelona, Barcelona, Spain
[5] Lilly Research Laboratories, Eli Lilly, Lilly Corporate Center, Indianapolis, IN, United States
[6] Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States
Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) Study Group, United States

Source

Critical care medicine. 2003, Vol 31, Num 3, pp 834-840, 7 p ; ref : 24 ref

CODEN

CCMDC7

ISSN

0090-3493

Scientific domain

Anesthesia, intensive care

Publisher

Lippincott, Hagerstown, MD

Publication country

United States

Document type

Article

Language

English

Keyword (fr)

Activité biologique Bactériose Chimiothérapie Essai clinique phase III Homme Infusion Insuffisance organique multiple Morbidité Protéine C réactive Protéine recombinante Septique syndrome Traitement Drotrecogin alfa Infection

Keyword (en)

Biological activity Bacteriosis Chemotherapy Phase III trial Human Infusion Multiple organ failure Morbidity C reactive protein Recombinant protein Sepsis syndrome Treatment Drotrecogin alfa Infection

Keyword (es)

Actividad biológica Bacteriosis Quimioterapia Ensayo clínico fase III Hombre Infusión Insuficiencia orgánica múltiple Morbilidad Proteína reactiva Proteína recombinante Séptico síndrome Tratamiento Infección

Classification

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B27 Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy / 002B27B Intensive care medicine / 002B27B10 Emergency and intensive care: infection, septic shock

Discipline

Anaesthesia. Reanimation. Transfusion. Cell therapy and gene therapy

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

14640128

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS