Reversible conformational change of tau2 epitope on exposure to detergent in glial cytoplasmic inclusions of multiple system atrophy
- Author
- SHIBUYA, Katsuhiko1 2 ; UCHIHARA, Toshiki2 ; NAKAMURA, Ayako2 ; ISHIYAMA, Miyako3 ; YAMAOKA, Keiko3 ; YAGISHITA, Saburo3 ; IWABUCHI, Kiyoshi1 ; KOSAKA, Kenji4
[1] Department of Neurology and Psychiatry, Kanagawa Rehabilitation Center, 516 Nanasawa Atsugi-shi, 243-0121 Kanagawa-ken, Japan
[2] Department of Neuropathology, Tokyo Metropolitan Institute for Neuroscience, 2-6 Musashi-dai, Fuchu, 183-8526 Tokyo, Japan
[3] Department of Pathology, Kanagawa Rehabilitation Center, 516 Nanasawa Atsugi-shi, 243-0121 Kanagawa-ken, Japan
[4] Department of Psychiatry, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, 236-0004 Yokohama, Japan - Source
Acta neuropathologica. 2003, Vol 105, Num 5, pp 508-514, 7 p ; ref : 38 ref
- Publisher
- Springer, Berlin
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Conformational change Detergent Glial cytoplasmic inclusions Reversible Tau2 epitope
- Keyword (fr)
- Adulte Atrophie multisystématisée Biologie moléculaire Cellule gliale Conformation Détergent Déterminant antigénique Immunohistochimie Inclusion Microscopie immunoélectronique Pathogénie Personne âgée Protéine tau Réversibilité Changement conformationnel Anatomopathologie Encéphale pathologie Homme Maladie dégénérative Système nerveux central pathologie Système nerveux pathologie
- Keyword (en)
- Adult Multiple system atrophy Molecular biology Glial cell Conformation Detergent Antigenic determinant Immunohistochemistry Inclusion Immunoelectron microscopy Pathogenesis Elderly Tau protein Reversibility Pathology Cerebral disorder Human Degenerative disease Central nervous system disease Nervous system diseases
- Keyword (es)
- Adulto Atrofia multisistematizada Biología molecular Célula glial Conformación Detergente Determinante antigénico Inmunohistoquímica Inclusión Microscopía inmunoelectrónica Patogenia Anciano Proteína tau Reversibilidad Anatomía patológica Encéfalo patología Hombre Enfermedad degenerativa Sistema nervosio central patología Sistema nervioso patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14695147
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00401-003-0675-4 
https://dx.doi.org/10.1007/s00401-003-0675-4
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