Effects of aprepitant on the pharmacokinetics of ondansetron and granisetron in healthy subjects
- Author
- BLUM, Robert A1 ; MAJUMDAR, Anup2 ; GOTTESDIENER, Kevin M2 ; HUSTAD, Carolyn M2 ; LATES, Christian1 ; KRAFT, Walter K3 ; VAN BUREN, Sandi3 ; WALDMAN, Scott A3 ; GREENBERG, Howard E3 ; MCCREA, Jacqueline2 ; BUSILLO, John2 ; ORLOWSKI, Laura H2 ; PANEBIANCO, Deborah2 ; HESNEY, Michael2 ; PETTY, Kevin J2 ; GOLDBERG, Michael R2 ; MURPHY, M. Gail2
[1] Buffalo Clinical Research Center, Buffalo, New York, United States
[2] Merck Research Laboratories, West Point, Pennsylvania, United States
[3] Division of Clinical Pharmacology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States - Source
Clinical therapeutics. 2003, Vol 25, Num 5, pp 1407-1419, 13 p ; ref : 32 ref
- ISSN
- 0149-2918
- Scientific domain
- Pharmacology drugs
- Publisher
- Excerpta Medica, Belle Mead, NJ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- 5-HT3-receptor antagonist CINV chemotherapy emesis
- Keyword (fr)
- Antagoniste sérotonine Antagoniste Antiémétique Association médicamenteuse Granisétron Individu sain Interaction médicamenteuse Ondansétron Pharmacocinétique Récepteur sérotoninergique 5-HT3 Récepteur tachykinine NK1 Voie orale Aprepitant
- Keyword (en)
- Serotonin antagonist Antagonist Antiemetic Drug combination Granisetron Healthy subject Drug interaction Ondansetron Pharmacokinetics 5-HT3 Serotonine receptor NK1 Tachykinin receptor Oral administration
- Keyword (es)
- Antagonista serotonina Antagonista Antiemético Asociación medicamentosa Granisetrón Individuo sano Interacción medicamentosa Ondansetrón Farmacocinética Receptor serotoninérgico 5-HT3 Receptor taquikinina NK1 Vía oral
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02H Digestive system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14888034
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0149-2918(03)80128-5 
https://dx.doi.org/10.1016/S0149-2918(03)80128-5
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