Isolation of drugs active against mammalian prions using a yeast-based screening assay
- Author
- BACH, Stéphane1 ; TALAREK, Nicolas2 ; ANDRIEU, Thibault3 ; VIERFOND, Jean-Michel4 ; METTEY, Yvette4 ; GALONS, Hervé5 ; DORMONT, Dominique3 ; MEIJER, Laurent1 ; CULLIN, Christophe2 ; BLONDEL, Marc1
[1] C.N.R.S., Station Biologique, Cell Cycle Laboratory, place Georges Teissier, 29680 ROSCOFF, Bretagne, France
[2] IBGC, 1 rue Camille Saint-Saens, 33077 Bordeaux, France
[3] Service de Neurovirologie, CEA/CRSSA/EPHE, BP 6, 92265 Fontenay aux Roses, France
[4] Faculté de Médecine et de Pharmacie, 34 rue du Jardin des Plantes, BP 199, 86005 Poitiers, France
[5] Laboratoire de Chimie Organique 2, Université René Descartes, 4 avenue de l'Observatoire, 75270 Paris, France - Source
Nature biotechnology. 2003, Vol 21, Num 9, pp 1075-1081, 7 p ; ref : 34 ref
- CODEN
- NABIF9
- ISSN
- 1087-0156
- Scientific domain
- Biotechnology
- Publisher
- Nature, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Chlorpromazine Criblage Isolement Levure Mammalia Médicament Phénanthridine dérivé Prion Quinacrine kastelpaolitines Vertebrata
- Keyword (en)
- Chlorpromazine Screening Isolation Yeast Mammalia Drug Phenanthridine derivatives Prion Vertebrata
- Keyword (es)
- Clorpromazina Cernido Aislamiento Levadura Mammalia Medicamento Prión Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology / 002A31D Industrial applications and implications. Economical aspects / 002A31D01 Health. Pharmaceutical industry / 002A31D01C Production of active biomolecules / 002A31D01C8 Other active biomolecules
- Discipline
- Biotechnology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15118708
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nbt855 
https://dx.doi.org/10.1038/nbt855
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