Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators
- Author
- ELMORE, Steven W1 ; PRATT, John K1 ; MILLER, Loan1 ; TYREE, Curtis M2 ; MINER, Jeffrey N2 ; LANE, Ben1 ; COGHLAN, Michael J1 ; YUE MAO1 ; GREEN, Brian E1 ; ANDERSON, David D1 ; STASHKO, Michael A1 ; LIN, Chun W1 ; FALLS, Douglas1 ; NAKANE, Masaki1
[1] Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064-3500, United States
[2] New Leads Discovery and Transcription Research, Ligand Pharmaceuticals, Inc., San Diego, CA 92121, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 7, pp 1721-1727, 7 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antiinflammatoire Composé aromatique Composé tétracyclique Enantiomère(-) Facteur transcription Glucocorticoïde Homme Hétérocycle oxygène azote In vitro Modulation Mécanisme action Relation structure activité Stéroïde Stéréoisomère anti Benzopyranoquinoléine Cyclohexène dérivé [1]Benzopyrano[3,4-f]quinoléine(10-méthoxy-5-[1-méthylcyclohex-2-ényl]-2,2,4-triméthyl)
- Keyword (en)
- Antiinflammatory agent Aromatic compound Tetracyclic compound Enantiomer(-) Transcription factor Glucocorticoid Human Oxygen nitrogen heterocycle In vitro Modulation Mechanism of action Structure activity relation Steroid Anti stereoisomer
- Keyword (es)
- Antiinflamatorio Compuesto aromático Compuesto tetracíclico Enantiómero(-) Factor transcripción Glucocorticoide Hombre Heterociclo oxígeno nitrógeno In vitro Modulación Mecanismo acción Relación estructura actividad Esteroide Estereoisómero anti
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02L Bones, joints and connective tissue. Antiinflammatory agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15558811
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2004.01.044 
https://dx.doi.org/10.1016/j.bmcl.2004.01.044
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