Phosphatidylinositol-3-oH kinase/AKT and survivin pathways as critical targets for geranylgeranyltransferase I inhibitor-induced apoptosis
- Author
- DAN, Han C1 ; KUN JIANG1 2 ; COPPOLA, Domenico1 2 ; HAMILTON, Andrew3 ; NICOSIA, Santo V1 2 ; SEBTI, Said M2 4 ; CHENG, Jin Q1 2 4
[1] Department of Pathology, University of South Florida College of Medicine, Tampa, FL 33612, United States
[2] Department of Interdisciplinary Oncology, University of Sooth Florida College of Medicine, Tampa, FL 33612, United States
[3] Department of Chemistry, Yale University, New Haven, CT 06511, United States
[4] Drug Discovery Program, University of South Florida College of Medicine, H Lee Moffitt Cancer Center, Tampa, FL 33612, United States - Source
Oncogene (Basingstoke). 2004, Vol 23, Num 3, pp 706-715, 10 p ; ref : 42 ref
- ISSN
- 0950-9232
- Scientific domain
- Cell biology, histology; Medical oncology; Genetics
- Publisher
- Nature Publishing, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Akt GGTI P13K apoptosis ovarian cancer survivin
- Keyword (fr)
- Apoptose Carcinogenèse Inhibiteur Kinase Phosphatidylinositol Tumeur maligne Cancer de l'ovaire Protein kinase B Appareil génital femelle pathologie Enzyme Ovaire pathologie Transferases
- Keyword (en)
- Apoptosis Carcinogenesis Inhibitor Kinase Phosphatidylinositol Malignant tumor Ovarian cancer Protein kinase B Female genital diseases Enzyme Ovarian diseases Transferases
- Keyword (es)
- Apoptosis Carcinogénesis Inhibidor Kinase Fosfatidilinositol Tumor maligno Cáncer de ovario Protein kinase B Aparato genital hembra patología Enzima Ovario patología Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H05 Ageing, cell death
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20C Female genital diseases / 002B20C02 Tumors
- Discipline
- Gynecology. Andrology. Obstetrics Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 15673928
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.onc.1207171 
https://dx.doi.org/10.1038/sj.onc.1207171
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