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Oral administration of a low dose of midazolam (75 μg) as an in vivo probe for CYP3A activity

Author
EAP, Chin B1 ; BUCLIN, Thierry2 ; KERB, Reinhold3 ; CUCCHIA, Gianni1 ; ZULLINO, Daniele1 ; HUSTERT, Elisabeth3 ; BLEIBER, Gabriela4 ; POWELL GOLAY, Kerry1 ; AUBERT, Anne-Catherine1 ; BAUMANN, Pierre1 ; TELENTI, Amalio4
[1] Unit of Biochemistry and Clinical Psychopharmacology, Centre of Psychiatric Neurosciences, University Department of Adult Psychiatry, Prilly-Lausanne, Switzerland
[2] Department of Clinical Pharmacology, University Hospital of Lausanne, Switzerland
[3] EPIDAUROS Biotechnologie AG, Am Neuland 1, Bernried, Germany
[4] Division of Infectious Diseases, University Hospital of Lausanne, Switzerland
Source

European journal of clinical pharmacology. 2004, Vol 60, Num 4, pp 237-246, 10 p ; ref : 24 ref

ISSN
0031-6970
Scientific domain
Pharmacology drugs
Publisher
Springer, Berlin / Springer, Heidelberg
Publication country
Germany
Document type
Article
Language
English
Author keyword
CYP Midazolam Phenotyping
Keyword (fr)
Cytochrome P450 Dose faible Homme Hypnotique In vivo Isozyme Midazolam Sédatif Voie orale Benzodiazépine dérivé Enzyme
Keyword (en)
Cytochrome P450 Low dose Human Hypnotic In vivo Isozyme Midazolam Sedative Oral administration Benzodiazepine derivatives Enzyme
Keyword (es)
Citocromo P450 Dosis débil Hombre Hipnótico In vivo Isozima Midazolam Sedante Vía oral Benzodiazepina derivado Enzima
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
15867039

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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