Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference
- Author
- SUMIMOTO, Hidetoshi1 ; MIYAGISHI, Makoto2 ; MIYOSHI, Hiroyuki3 ; YAMAGATA, Shizuko1 ; SHIMIZU, Ayako1 ; TAIRA, Kazunari2 ; KAWAKAMI, Yutaka1
[1] Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
[2] Department of Chemistry and Biotechnology Sehool of Engineering, The University of Tokyo, Hongo, Tokyo 113-8656, Japan
[3] Sabteam for Manipulation of Cell Fate, BioResource Center, RIKEN Tsakaha Institute, 3-1-1 Koyadai, Tsukuba 305-0074, Japan - Source
Oncogene (Basingstoke). 2004, Vol 23, Num 36, pp 6031-6039, 9 p ; ref : 40 ref
- ISSN
- 0950-9232
- Scientific domain
- Cell biology, histology; Medical oncology; Genetics
- Publisher
- Nature Publishing, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- BRAF MAPK RNAi gene therapy lentiviral vector melanoma
- Keyword (fr)
- Carcinogenèse Croissance Gène onc cellulaire Inactivation Inhibition Lentivirus Mitogen-activated protein kinase Mutation Mélanome malin Protooncogène Silence expression génique Thérapie génique Vecteur RNA interférence Enzyme Retroviridae Tumeur maligne Virus
- Keyword (en)
- Carcinogenesis Growth C-Onc gene Inactivation Inhibition Lentivirus Mitogen-activated protein kinase Mutation Malignant melanoma Protooncogene Gene silencing Gene therapy Vector RNA interference Enzyme Retroviridae Malignant tumor Virus
- Keyword (es)
- Carcinogénesis Crecimiento Gen onc celular Inactivación Inhibición Lentivirus Mitogen-activated protein kinase Mutación Melanoma maligno Protooncogen Silencio expresión genética Terapia génica Vector Enzima Retroviridae Tumor maligno Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology / 002A31D Industrial applications and implications. Economical aspects / 002A31D01 Health. Pharmaceutical industry / 002A31D01D Gene therapy
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B08 Dermatology / 002B08A Tumors of the skin and soft tissue. Premalignant lesions
- Discipline
- Biotechnology Dermatology Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16019995
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.onc.1207812 
https://dx.doi.org/10.1038/sj.onc.1207812
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