Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitors
- Author
- CARLOMAGNO, Francesca1 ; GUIDA, Teresa1 ; ANAGANTI, Suresh1 ; VECCHIO, Giancarlo1 ; FUSCO, Alfredo1 ; RYAN, Anderson J2 ; BILLAUD, Marc3 ; SANTORO, Massimo1
[1] Dipartmtento di Biologia e Patologia Cellulare e Molecolare, University 'Federico II', clo Istituto di Endocrinologia ed Oncologia Sperimentale del CNR, via S. Pansini 5, Napoli, Italy
[2] Cancer Discovery, Astra Zeneca Mereside, Alderley Park, Macclesfield, Cheshire, United Kingdom
[3] Laboratoire de Genetique, CNRS, Lyon, France - Source
Oncogene (Basingstoke). 2004, Vol 23, Num 36, pp 6056-6063, 8 p ; ref : 1 p.1/4
- ISSN
- 0950-9232
- Scientific domain
- Cell biology, histology; Medical oncology; Genetics
- Publisher
- Nature Publishing, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- MEN2 RET thyroid tyrosine kinase inhibitors
- Keyword (fr)
- Carcinogenèse Carcinome médullaire Inhibiteur enzyme Kinase Mutation Protein-tyrosine kinase Récepteur membranaire Résistance traitement Thyroïde Enzyme Thyroïde pathologie Transferases
- Keyword (en)
- Carcinogenesis Medullary carcinoma Enzyme inhibitor Kinase Mutation Protein-tyrosine kinase Membrane receptor Treatment resistance Thyroid gland Enzyme Thyroid diseases Transferases
- Keyword (es)
- Carcinogénesis Carcinoma medular Inhibidor enzima Kinase Mutación Protein-tyrosine kinase Receptor membrana Resistencia tratamiento Tiroides Enzima Tiroides patología Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes
- Discipline
- Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16019998
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.onc.1207810 
https://dx.doi.org/10.1038/sj.onc.1207810
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