Synthesis and potent antitumor activities of novel 1,3,5-cis, cis-triaminocyclohexane N-pyridyl derivatives
- Auteur
- CHONG, Hyun-Soon1 ; TORTI, Suzy V2 3 ; MA, Rong2 3 ; TORTI, Frank M3 4 ; BRECHBIEL, Martin W1
[1] Chemistry, Section, National Cancer Institute, NIH, Bethesda, Maryland, United States
[2] Department of Cancer Biology, Wake Forest University, Winston Salem, North Carolina, United States
[3] Comprehensive Cancer Center, Wake Forest University, Winston Salem, North Carolina, United States
[4] Department of Biochemistry, Wake Forest University, Winston Salem, North Carolina, United States - Source
Journal of medicinal chemistry (Print). 2004, Vol 47, Num 21, pp 5230-5234, 5 p ; ref : 14 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Domaine scientifique
- Pharmacology drugs
- Editeur
- American Chemical Society, Washington, DC
- Pays de publication
- United States
- Type de document
- Article
- Langue
- English
- Mot clé (fr)
- Activité biologique Anticancéreux Chélateur Cyclohexane dérivé Fer In vitro Lignée HeLa Lignée cellulaire Pyridine dérivé Stéréoisomère cis Synthèse chimique Cyclohexane(1,3,5-tris[5-(3-[t-butoxycarbonylamino]propylcarbamoyl)-2-pyridylméthylamino])
- Mot clé (en)
- Biological activity Antineoplastic agent Chelating agent Cyclohexane derivatives Iron In vitro Hela cell line Cell line Pyridine derivatives Cis stereoisomer Chemical synthesis
- Mot clé (es)
- Actividad biológica Anticanceroso Quelante Ciclohexano derivado Hierro In vitro Célula HeLa Línea celular Piridina derivado Estereoisómero cis Síntesis química
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B02 Pharmacologie. Traitements medicamenteux / 002B02R Anticancéreux / 002B02R01 Généralités
- Discipline
- Pharmacological treatments
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 16200657
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm040076w 
https://dx.doi.org/10.1021/jm040076w
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