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Structure-function of cytochromes P450 and flavin-containing monooxygenases : Implications for drug metabolism

Author
HALPERT, J. R1 ; DOMANSKI, T. L1 ; SIBBESEN, O4 ; WYATT, W. K2 ; ZHOUPENG ZHENG4 ; ADALI, O2 ; BIAGINI, C. P2 ; COSME, J3 ; DIERKS, E. A4 ; JOHNSON, E. F3 ; JONES, J. P5 ; ORTIZ DE MONTELLANO, P4 ; PHILPOT, R. M2
[1] Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, United States
[2] Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, United States
[3] Department of Molecular and Experimental Medicine NX-4, Scripps Research Institute, United States
[4] Department of Chemistry and Pharmacology, School of Pharmacy, University of California at San Francisco, United States
[5] Department of Chemistry, Washington State University, United States
Source

Drug metabolism and disposition. 1998, Vol 26, Num 12, pp 1223-1231 ; ref : 1 p.1/4

CODEN
DMDSAI
ISSN
0090-9556
Scientific domain
Pharmacology drugs
Publisher
American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Cytochrome P450 In vitro Isozyme Modèle moléculaire Mutagenèse dirigée Médicament Métabolisme Relation structure fonction Unspecific monooxygenase Enzyme Oxidoreductases
Keyword (en)
Cytochrome P450 In vitro Isozyme Molecular model Site directed mutagenesis Drug Metabolism Structure function relationship Unspecific monooxygenase Enzyme Oxidoreductases
Keyword (es)
Citocromo P450 In vitro Isozima Modelo molecular Mutagénesis dirigida Medicamento Metabolismo Relación estructura función Unspecific monooxygenase Enzima Oxidoreductases
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02E Enzymes and enzyme inhibitors / 002A02E08 Miscellaneous

Discipline
Analytical, structural and metabolic biochemistry
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
1640009

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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