Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
- Author
- GORGOUILS, Wassilis G1 ; VASSILLOU, Leandros-Vasslllos F1 ; KLETSAS, Dimitris6 ; YONETA, Aklhiro3 ; HERLYN, Meenhard3 ; KITTAS, Christos1 ; HALAZONETIS, Thanos D3 7 ; KARAKALDOS, Panaglotis1 ; ZACHARATOS, Panayotis1 ; KOTSINAS, Athanasslos1 ; LILOGIOU, Triantafillos2 ; VENERE, Monica3 4 ; DITUILLO, Richard A3 4 ; KASTRINAKIS, Nikolaos G1 ; LEVY, Brynn5
[1] Department of Histology and Embryology, School of Medicine, University of Athens, Athens 11527, Greece
[2] Roy Castle Lung Cancer Research Programme, Cancer Research Center, University of Liverpool, Liverpool L3 9TA, United Kingdom
[3] The Wistar Institute, Philadelphia, Pennsylvania 19104-4268, United States
[4] Graduate Group in Biomedical Sciences, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States
[5] Department of Human Genetics, Mount Sinai School of Medicine, New York, New York 10029, United States
[6] Institute of Biology, National Centre of Scientific Research 'Demokritos', Athens 15310, Greece
[7] Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States - Source
Nature (London). 2005, Vol 434, Num 7035, pp 907-913, 7 p ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Cancérologie Carcinogenèse Cassure bicaténaire DNA Gène TP53 Gène suppresseur tumeur Homme Lésion précancéreuse Lésion Point contrôle Instabilité génétique Génétique
- Keyword (en)
- Cancerology Carcinogenesis Double strand break DNA TP53 Gene Tumor suppressor gene Human Premalignant lesion Lesion Control point Genetic instability Genetics
- Keyword (es)
- Cancerología Carcinogénesis Ruptura bicatenaria DNA Gen TP53 Gen supresor tumor Hombre Lesión precancerosa Lesión Punto control Genética
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04E Carcinogenesis, carcinogens and anticarcinogens / 002B04E01 General aspects
- Discipline
- Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16698313
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature03485 
https://dx.doi.org/10.1038/nature03485
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