Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hürthle cell) tumours of the thyroid
- Author
- MAXIMO, V1 ; BOTELHO, T1 ; WILLIAMS, D7 ; SOBRINHO-SIMOES, M1 3 8 ; CAPELA, J2 ; SOARES, P1 3 ; LIMA, J1 ; TAVEIRA, A1 2 ; AMARO, T4 ; BARBOSA, A. P5 ; PRETO, A1 ; HARACH, H. R6
[1] IPATIMUP-Institute of Molecular Pathology and Immunology of the University of Porto, Rua Dr Roberto Frias s/n, 4200-465 Porto, Portugal
[2] Department of Surgery, Hospital São João, Porto, Portugal
[3] Department of Pathology, Medical Faculty of Porto, Porto, Portugal
[4] Department of Pathology, Portuguese Oncology Institute, Porto, Portugal
[5] Department of Endocrinology, Portuguese Oncology Institute, Porto, Portugal
[6] Pathology Service, 'Dr A Onãtivia' Hospital, Salta, Argentina
[7] Strangeways Research Laboratory, University of Cambridge, Cambridge, United Kingdom
[8] Department of Pathology, Hospital São João, Porto, Portugal - Source
British journal of cancer. 2005, Vol 92, Num 10, pp 1892-1898, 7 p ; ref : 1 p.1/4
- CODEN
- BJCAAI
- ISSN
- 0007-0920
- Scientific domain
- Medical oncology
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- GRIM-19 Hürthle cell tumours familial thyroid carcinoma mitochondrial proteins thyroid cancer
- Keyword (fr)
- Apoptose Cancer thyroïde Cancérologie Cellule tumorale Gène Génétique Lignée germinale Mitochondrie Mort cellulaire Mutation somatique Métabolisme Protéine Carcinome thyroïde Endocrinopathie Glande endocrine Thyroïde pathologie Tumeur maligne
- Keyword (en)
- Apoptosis Thyroid cancer Cancerology Tumor cell Gene Genetics Germ line Mitochondria Cell death Somatic mutation Metabolism Protein Thyroid carcinoma Endocrinopathy Endocrine gland Thyroid diseases Malignant tumor
- Keyword (es)
- Apoptosis Cáncer de la tiroides Cancerología Célula tumoral Gen Genética Línea germinal Mitocondria Muerte celular Mutación somática Metabolismo Proteína Carcinoma tiroides Endocrinopatía Glándula endocrina Tiroides patología Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21C Thyroid. Thyroid axis (diseases) / 002B21C02 Malignant tumors
- Discipline
- Endocrinopathies Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16833332
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.bjc.6602547 
https://dx.doi.org/10.1038/sj.bjc.6602547
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