Angiotensin-converting enzyme 2 protects from severe acute lung failure
- Author
- IMAI, Yumiko1 ; KUBA, Keiji1 ; CRACKOWER, Michael A4 ; FUKAMIZU, Akiyoshi5 ; HUI, Chi-Chung6 ; HEIN, Lutz7 ; UHLIG, Stefan8 ; SLUTSKY, Arthur S9 ; CHENGYU JIANG2 ; PENNINGER, Josef M1 ; SHUAN RAO2 ; YI HUAN2 ; FENG GUO2 ; BIN GUAN2 ; PENG YANG2 ; SARAO, Renu1 ; WADA, Teiji1 ; LEONG-POI, Howard3
[1] MBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna 1030, Austria
[2] National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China
[3] Department of Cardiology, St. Michael's Hospital, Toronto, Ontario MSB 1W8, Canada
[4] Department of Biochemistry and Molecular Biology, Merck Frosst Centre for Therapeutic Research, Montreal, Quebec H3R 4P8, Canada
[5] Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba 305-8577, Japan
[6] Program in Developmental Biology, The Hospital for Sick Children and Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario MG5 1X8, Canada
[7] Department of Pharmacology, University of Freiburg, Freiburg 79104, Germany
[8] Division of Pulmonary Pharmacology, Research Center Borstel, Borstel 23845, Germany
[9] Department of Medicine and Interdepartmental Division of Critical Care, University of Toronto, St. Michael's Hospital, Toronto, Ontario MSB 1W8, Canada - Source
Nature (London). 2005, Vol 436, Num 7047, pp 112-116, 5 p ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Chimiothérapie Détresse respiratoire Etiologie Homme Inhibiteur angiotensin converting enzyme Peptidyl-dipeptidase A Protéine recombinante Souris Syndrome respiratoire aigu sévère ACE2 Enzyme Hydrolases Infection Mammalia Peptidases Peptidyl-dipeptidases Rodentia Vertebrata Virose
- Keyword (en)
- Animal Chemotherapy Respiratory distress Etiology Human ACE inhibitor Peptidyl-dipeptidase A Recombinant protein Mouse Severe acute respiratory syndrome Enzyme Hydrolases Infection Mammalia Peptidases Peptidyl-dipeptidases Rodentia Vertebrata Viral disease
- Keyword (es)
- Animal Quimioterapia Trastorno respiratorio Etiología Hombre Inhibidor angiotensin converting enzyme Peptidyl-dipeptidase A Proteína recombinante Ratón Síndrome respiratorio agudo severo Enzima Hydrolases Infección Mammalia Peptidases Peptidyl-dipeptidases Rodentia Vertebrata Virosis
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05C Viral diseases / 002B05C02 Human viral diseases / 002B05C02C Viral diseases of the respiratory system and ent viral diseases
- Discipline
- Infectious pathology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 16921001
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1038/nature03712 
https://dx.doi.org/10.1038/nature03712
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:19:\"10.1038\/nature03712\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:71:\"Angiotensin-converting enzyme 2 protects from severe acute lung failure\";s:9:\"\u0000*\u0000jtitle\";s:15:\"Nature (London)\";s:9:\"\u0000*\u0000stitle\";s:14:\"Nature (Lond.)\";s:7:\"\u0000*\u0000date\";s:4:\"2005\";s:9:\"\u0000*\u0000volume\";s:3:\"436\";s:8:\"\u0000*\u0000issue\";s:4:\"7047\";s:8:\"\u0000*\u0000spage\";s:3:\"112\";s:8:\"\u0000*\u0000epage\";s:3:\"116\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0028-0836\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:4:\"IMAI\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Yumiko\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:17:{i:0;s:11:\"KUBA, Keiji\";i:1;s:20:\"CRACKOWER, Michael A\";i:2;s:18:\"FUKAMIZU, Akiyoshi\";i:3;s:14:\"HUI, Chi-Chung\";i:4;s:10:\"HEIN, Lutz\";i:5;s:13:\"UHLIG, Stefan\";i:6;s:17:\"SLUTSKY, Arthur S\";i:7;s:13:\"CHENGYU JIANG\";i:8;s:18:\"PENNINGER, Josef M\";i:9;s:9:\"SHUAN RAO\";i:10;s:7:\"YI HUAN\";i:11;s:8:\"FENG GUO\";i:12;s:8:\"BIN GUAN\";i:13;s:9:\"PENG YANG\";i:14;s:11:\"SARAO, Renu\";i:15;s:11:\"WADA, Teiji\";i:16;s:17:\"LEONG-POI, Howard\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"NATUAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:71:\"Angiotensin-converting enzyme 2 protects from severe acute lung failure\";s:8:\"\u0000*\u0000place\";s:6:\"London\";s:6:\"\u0000*\u0000pub\";s:17:\"Nature Publishing\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"5\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:19:\"10.1038\/nature03712\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:71:\"Angiotensin-converting enzyme 2 protects from severe acute lung failure\";s:9:\"\u0000*\u0000jtitle\";s:15:\"Nature (London)\";s:9:\"\u0000*\u0000stitle\";s:14:\"Nature (Lond.)\";s:7:\"\u0000*\u0000date\";s:4:\"2005\";s:9:\"\u0000*\u0000volume\";s:3:\"436\";s:8:\"\u0000*\u0000issue\";s:4:\"7047\";s:8:\"\u0000*\u0000spage\";s:3:\"112\";s:8:\"\u0000*\u0000epage\";s:3:\"116\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0028-0836\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:4:\"IMAI\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Yumiko\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:17:{i:0;s:11:\"KUBA, Keiji\";i:1;s:20:\"CRACKOWER, Michael A\";i:2;s:18:\"FUKAMIZU, Akiyoshi\";i:3;s:14:\"HUI, Chi-Chung\";i:4;s:10:\"HEIN, Lutz\";i:5;s:13:\"UHLIG, Stefan\";i:6;s:17:\"SLUTSKY, Arthur S\";i:7;s:13:\"CHENGYU JIANG\";i:8;s:18:\"PENNINGER, Josef M\";i:9;s:9:\"SHUAN RAO\";i:10;s:7:\"YI HUAN\";i:11;s:8:\"FENG GUO\";i:12;s:8:\"BIN GUAN\";i:13;s:9:\"PENG YANG\";i:14;s:11:\"SARAO, Renu\";i:15;s:11:\"WADA, Teiji\";i:16;s:17:\"LEONG-POI, Howard\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"NATUAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:71:\"Angiotensin-converting enzyme 2 protects from severe acute lung failure\";s:8:\"\u0000*\u0000place\";s:6:\"London\";s:6:\"\u0000*\u0000pub\";s:17:\"Nature Publishing\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"5\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:19:\"10.1038\/nature03712\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:19:\"10.1038\/nature03712\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:71:\"Angiotensin-converting enzyme 2 protects from severe acute lung failure\";s:9:\"\u0000*\u0000jtitle\";s:15:\"Nature (London)\";s:9:\"\u0000*\u0000stitle\";s:14:\"Nature (Lond.)\";s:7:\"\u0000*\u0000date\";s:4:\"2005\";s:9:\"\u0000*\u0000volume\";s:3:\"436\";s:8:\"\u0000*\u0000issue\";s:4:\"7047\";s:8:\"\u0000*\u0000spage\";s:3:\"112\";s:8:\"\u0000*\u0000epage\";s:3:\"116\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0028-0836\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:4:\"IMAI\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Yumiko\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:17:{i:0;s:11:\"KUBA, Keiji\";i:1;s:20:\"CRACKOWER, Michael A\";i:2;s:18:\"FUKAMIZU, Akiyoshi\";i:3;s:14:\"HUI, Chi-Chung\";i:4;s:10:\"HEIN, Lutz\";i:5;s:13:\"UHLIG, Stefan\";i:6;s:17:\"SLUTSKY, Arthur S\";i:7;s:13:\"CHENGYU JIANG\";i:8;s:18:\"PENNINGER, Josef M\";i:9;s:9:\"SHUAN RAO\";i:10;s:7:\"YI HUAN\";i:11;s:8:\"FENG GUO\";i:12;s:8:\"BIN GUAN\";i:13;s:9:\"PENG YANG\";i:14;s:11:\"SARAO, Renu\";i:15;s:11:\"WADA, Teiji\";i:16;s:17:\"LEONG-POI, Howard\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"NATUAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:71:\"Angiotensin-converting enzyme 2 protects from severe acute lung failure\";s:8:\"\u0000*\u0000place\";s:6:\"London\";s:6:\"\u0000*\u0000pub\";s:17:\"Nature Publishing\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"5\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:11:\"BaseOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:19:\"10.1038\/nature03712\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:71:\"Angiotensin-converting enzyme 2 protects from severe acute lung failure\";s:9:\"\u0000*\u0000jtitle\";s:15:\"Nature (London)\";s:9:\"\u0000*\u0000stitle\";s:14:\"Nature (Lond.)\";s:7:\"\u0000*\u0000date\";s:4:\"2005\";s:9:\"\u0000*\u0000volume\";s:3:\"436\";s:8:\"\u0000*\u0000issue\";s:4:\"7047\";s:8:\"\u0000*\u0000spage\";s:3:\"112\";s:8:\"\u0000*\u0000epage\";s:3:\"116\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0028-0836\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:4:\"IMAI\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Yumiko\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:17:{i:0;s:11:\"KUBA, Keiji\";i:1;s:20:\"CRACKOWER, Michael A\";i:2;s:18:\"FUKAMIZU, Akiyoshi\";i:3;s:14:\"HUI, Chi-Chung\";i:4;s:10:\"HEIN, Lutz\";i:5;s:13:\"UHLIG, Stefan\";i:6;s:17:\"SLUTSKY, Arthur S\";i:7;s:13:\"CHENGYU JIANG\";i:8;s:18:\"PENNINGER, Josef M\";i:9;s:9:\"SHUAN RAO\";i:10;s:7:\"YI HUAN\";i:11;s:8:\"FENG GUO\";i:12;s:8:\"BIN GUAN\";i:13;s:9:\"PENG YANG\";i:14;s:11:\"SARAO, Renu\";i:15;s:11:\"WADA, Teiji\";i:16;s:17:\"LEONG-POI, Howard\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"NATUAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:71:\"Angiotensin-converting enzyme 2 protects from severe acute lung failure\";s:8:\"\u0000*\u0000place\";s:6:\"London\";s:6:\"\u0000*\u0000pub\";s:17:\"Nature Publishing\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"5\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Base Search access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:19:\"10.1038\/nature03712\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:71:\"Angiotensin-converting enzyme 2 protects from severe acute lung failure\";s:9:\"\u0000*\u0000jtitle\";s:15:\"Nature (London)\";s:9:\"\u0000*\u0000stitle\";s:14:\"Nature (Lond.)\";s:7:\"\u0000*\u0000date\";s:4:\"2005\";s:9:\"\u0000*\u0000volume\";s:3:\"436\";s:8:\"\u0000*\u0000issue\";s:4:\"7047\";s:8:\"\u0000*\u0000spage\";s:3:\"112\";s:8:\"\u0000*\u0000epage\";s:3:\"116\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0028-0836\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:4:\"IMAI\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Yumiko\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:17:{i:0;s:11:\"KUBA, Keiji\";i:1;s:20:\"CRACKOWER, Michael A\";i:2;s:18:\"FUKAMIZU, Akiyoshi\";i:3;s:14:\"HUI, Chi-Chung\";i:4;s:10:\"HEIN, Lutz\";i:5;s:13:\"UHLIG, Stefan\";i:6;s:17:\"SLUTSKY, Arthur S\";i:7;s:13:\"CHENGYU JIANG\";i:8;s:18:\"PENNINGER, Josef M\";i:9;s:9:\"SHUAN RAO\";i:10;s:7:\"YI HUAN\";i:11;s:8:\"FENG GUO\";i:12;s:8:\"BIN GUAN\";i:13;s:9:\"PENG YANG\";i:14;s:11:\"SARAO, Renu\";i:15;s:11:\"WADA, Teiji\";i:16;s:17:\"LEONG-POI, Howard\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"NATUAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:71:\"Angiotensin-converting enzyme 2 protects from severe acute lung failure\";s:8:\"\u0000*\u0000place\";s:6:\"London\";s:6:\"\u0000*\u0000pub\";s:17:\"Nature Publishing\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"5\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
