Antifungal agents. 11. N-substituted derivatives of 1-[(aryl)(4-aryl-1H-pyrrol-3-yl)methyl]-1H -imidazole : Synthesis, anti-Candida activity, and QSAR studies
- Author
- DI SANTO, Roberto1 ; TAFI, Andrea2 ; COSTI, Roberta1 ; BOTTA, Maurizo2 ; ARTICO, Marino1 ; CORELLI, Federico2 ; FORTE, Michela1 ; CAPORUSCIO, Fabiana3 ; ANGIOLELLA, Letizia4 ; PALAMARA, Teresa4
[1] Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Studi Farmaceutici, Università di Roma La Sapiema, P.le Aldo Moro 5, 00185 Roma, Italy
[2] Dipartimento Farmaco Chimico Tecnologico, Università di Siena, Via Aldo Moro, S. Miniato, 53100 Siena, Italy
[3] Dipartimento di Studi di Chimica e Tecnologia delle Sostanze Biologicamente Attive, Università di Roma La Sapienza, P.le Aldo Moro 5, 00185 Roma, Italy
[4] Istituto di Microbiologia, Università di Roma La Sapienza, P.le Aldo Moro 5, 00185 Roma, Italy - Source
Journal of medicinal chemistry (Print). 2005, Vol 48, Num 16, pp 5140-5153, 14 p ; ref : 52 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antifongique Benzène dérivé Candida albicans Hétérocycle azote Imidazole dérivé In vitro Modèle moléculaire Modélisation Naphtalène dérivé Prédiction Pyrrole dérivé Relation structure activité Synthèse chimique QSAR Chlore Composé organique Fungi Imperfecti Fungi Thallophyta
- Keyword (en)
- Antifungal agent Benzene derivatives Candida albicans Nitrogen heterocycle Imidazole derivatives In vitro Molecular model Modeling Naphthalene derivatives Prediction Pyrrole derivatives Structure activity relation Chemical synthesis Chlorine Organic compounds Fungi Imperfecti Fungi Thallophyta
- Keyword (es)
- Antifúngico Benceno derivado Candida albicans Heterociclo nitrógeno Imidazol derivado In vitro Modelo molecular Modelización Naftaleno derivado Predicción Pirrol derivado Relación estructura actividad Síntesis química Cloro Compuesto orgánico Fungi Imperfecti Fungi Thallophyta
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S04 Antifungal agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17021596
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm048997u 
https://dx.doi.org/10.1021/jm048997u
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