Structural elucidation of A-74528, an inhibitor for 2',5' -phosphodiesterase isolated from Streptomyces sp
- Author
- FUJITA, Yoko1 ; KASUYA, Atsushi1 ; MATSUSHITA, Yoichi1 ; SUGA, Miwa1 ; KIZUKA, Masaaki1 ; LIJIMA, Yasuteru1 ; OGITA, Takeshi1
[1] Sankyo R&D Facility, Sankyo Co. Ltd., 2-58, Hiromachi 1-chome, Shinagawa-ku, Tokyo 140-8710, Japan - Source
Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 19, pp 4317-4321, 5 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- A-74528 Inhibitor: Molecular-mechanics calculation NMR Phosphodiesterase Polyketide Structure elucidation
- Keyword (fr)
- Analyse structurale Chaîne latérale Composé aromatique Composé polycyclique Configuration relative Conformation Etude théorique Inhibiteur enzyme Isolement Modélisation Métabolite Méthode champ force Origine microbienne Phosphoric diester hydrolases Polycétide Spectrométrie RMN Streptomyces A 74528 Pyran-2-one dérivé Actinomycetales Actinomycetes Bactérie Enzyme Esterases Hydrolases Streptomycetaceae
- Keyword (en)
- Structural analysis Side chain Aromatic compound Polycyclic compound Relative configuration Conformation Theoretical study Enzyme inhibitor Isolation Modeling Metabolite Force field method Microbial origin Phosphoric diester hydrolases Polyketide NMR spectrometry Streptomyces Actinomycetales Actinomycetes Bacteria Enzyme Esterases Hydrolases Streptomycetaceae
- Keyword (es)
- Análisis estructural Cadena lateral Compuesto aromático Compuesto policíclico Configuración relativa Conformación Estudio teórico Inhibidor enzima Aislamiento Modelización Metabolito Método campo fuerza Origen microbiano Phosphoric diester hydrolases Policetido Espectrometría RMN Streptomyces Actinomycetales Actinomycetes Bacteria Enzima Esterases Hydrolases Streptomycetaceae
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05B Bacteriology / 002A05B01 General aspects
- Discipline
- Microbiology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17039224
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2005.06.047 
https://dx.doi.org/10.1016/j.bmcl.2005.06.047
