Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation
- Author
- VARELA, Ignacio1 ; CADINANOS, Juan1 ; TRYGGVASON, Karl2 ; FREIJE, José M. P1 ; LOPEZ-OTIN, Carlos1 ; PENDAS, Alberto M1 ; GUTIERREZ-FERNANDEZ, Ana1 ; FOLGUERAS, Alicia R1 ; SANCHEZ, Luis M1 ; ZHONGJUN ZHOU2 ; RODRIGUEZ, Francisco J1 ; STEWART, Colin L3 ; VEGA, José A4
[1] Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitano de Oncología, Spain
[2] Division of Matrix Biology, Department of Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden
[3] National Cancer Institute, Frederick, Maryland 21702, United States
[4] Departamento de Morfología y Blología Celular, Universidad de Oviedo, 33006 Oviedo, Spain - Source
Nature (London). 2005, Vol 437, Num 7058, pp 564-568, 5 p ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Accumulation biologique Animal Homme Metalloendopeptidases Mutation Protéine p53 Souris Stress Sénescence Enzyme Hydrolases Mammalia Peptidases Rodentia Vertebrata
- Keyword (en)
- Biological accumulation Animal Human Metalloendopeptidases Mutation p53 Protein Mouse Stress Senescence Enzyme Hydrolases Mammalia Peptidases Rodentia Vertebrata
- Keyword (es)
- Acumulación biológica Animal Hombre Metalloendopeptidases Mutación Proteína p53 Ratón Estrés Senescencia Enzima Hydrolases Mammalia Peptidases Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A16 Vertebrates: anatomy and physiology, studies on body, several organs or systems / 002A16B Development. Metamorphosis. Moult. Ageing
- Discipline
- Vertebrates : anatomy and physiology, studies on body, several organs or systems
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17124120
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature04019 
https://dx.doi.org/10.1038/nature04019
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