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Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE : Further evidence for survival and safety and implications for early treatment

Author
VINCENT, Jean-Louis1 ; BERNARD, Gordon R2 ; WONG, Kar9 ; SUNDIN, David P9 ; TURLO, Mary Ann9 ; JANES, Jonathan9 ; BEALE, Richard3 ; DOIG, Christopher4 ; PUTENSEN, Christian5 ; DHAINAUT, Jean-Francois6 ; ARTIGAS, Antonio7 ; FUMAGALLI, Roberto8 ; MACIAS, William; WRIGHT, Theressa9
[1] Department of Intensive Care, Erasme University Hospital and University of Brussels, Brussels, Belgium
[2] Division of Allergy, Pulmonary and Critical Care Medicine Vanderbit University School of Medicine, Nashville, TN, United States
[3] Intensive Care Unit, Guy's and St Thomas' Hospital, London, United Kingdom
[4] Departments of Critical Care Medicine, Medicine and Community Heath Sciences, University of Calgary, Calgary, AB, Canada
[5] Department of Anesthesia and Intensive Care Medicine, University of Bonn, Bonn, Germany
[6] Service de Réanimation Médicale, Centre Hospitalo-Universitaire Cochin Port-Royal, AP-HP, Paris V University, Paris, France
[7] Critical Care Center, Sabadell Hospital, Red CIRA C03/063 University Institute Parc Tauli, Autonomous University of Barcelona, Sabadell, Spain
[8] Facolta di Medicina e Chimrgia, Università degli Studi di Milano-Bicocca, Dipartimento di Anestesia e Rianimazione, Ospedali Riuniti di Bergamo, Italy
[9] Ully Research Laboratories, Eli Lilly, Indianapolis, IN, United States
ENHANCE Study Group
Source

Critical care medicine. 2005, Vol 33, Num 10, pp 2266-2277, 12 p ; ref : 14 ref

CODEN
CCMDC7
ISSN
0090-3493
Scientific domain
Anesthesia, intensive care
Publisher
Lippincott, Hagerstown, MD
Publication country
United States
Document type
Article
Language
English
Author keyword
ENHANCE activated protein C clinical trial drotrecogin alfa (activated) early treatment severe sepsis
Keyword (fr)
Anticoagulant Drotrécogine alfa Infection Protéine C Réanimation Septique syndrome Soin intensif Survie Traitement
Keyword (en)
Anticoagulant Drotrecogin alfa Infection Protein C Resuscitation Sepsis syndrome Intensive care Survival Treatment
Keyword (es)
Anticoagulante Drotrecogina alfa Infección Proteína C Reanimación Séptico síndrome Cuidado intensivo Sobrevivencia Tratamiento
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02G Blood. Blood coagulation. Reticuloendothelial system

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B27 Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy / 002B27B Intensive care medicine / 002B27B10 Emergency and intensive care: infection, septic shock

Discipline
Anaesthesia. Reanimation. Transfusion. Cell therapy and gene therapy Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17192454

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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