N-methyl-5-tert-butyltryptamine : A novel, highly potent 5-HT1D receptor agonist
- Author
- XU, Y.-C1 ; SCHAUS, J. M1 ; WALKER, C1 ; KRUSHINSKI, J1 ; ADHAM, N2 ; ZGOMBICK, J. M2 ; LIANG, S. X1 ; KOHLMAN, D. T1 ; AUDIA, J. E1
[1] Discovery Chemistry Research, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana 46285, United States
[2] Synaptic Pharmaceutical Corporation, 215 College Road, Paramus, New Jersey 07652, United States - Source
Journal of medicinal chemistry (Print). 1999, Vol 42, Num 3, pp 526-531 ; ref : 22 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Affinité Agoniste Amine Antimigraineux Composé aromatique Composé bicyclique Homme Hétérocycle azote In vitro Relation structure activité Récepteur sérotoninergique 5-HT1 Synthèse chimique Indole(5-alkyl-3-[2-aminoéthyl]) Indole(5-t-butyl-3-[2-(méthylamino)éthyl]) Récepteur sérotoninergique 5-HT1D Tryptamine dérivé
- Keyword (en)
- Affinity Agonist Amine Antimigrainous agent Aromatic compound Bicyclic compound Human Nitrogen heterocycle In vitro Structure activity relation 5-HT1 Serotonine receptor Chemical synthesis
- Keyword (es)
- Afinidad Agonista Amina Agente antimigrañoso Compuesto aromático Compuesto bicíclico Hombre Heterociclo nitrógeno In vitro Relación estructura actividad Receptor serotoninérgico 5-HT1 Síntesis química
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09C Serotoninergic system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1722448
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm9805945 
https://dx.doi.org/10.1021/jm9805945
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