Differential inhibition of thrombin activity and thrombin generation by a synthetic direct thrombin inhibitor (Napsagatran, Ro 46-6240) and unfractionated heparin in patients with deep vein thrombosis
- Author
- BOUNAMEAUX, H1 ; EHRINGER, H2 ; GAST, A3 ; HULTING, J4 ; RASCHE, H5 ; RAPOLD, H. J3 ; REBER, G1 ; TSCHOPP, T. B3
[1] Coordinating Center of the ADVENT Study (Division of Angiology and Hemostasis, University Hospital of Geneva, Geneva, Switzerland
[2] University Hospital of Vienna, Austria
[3] University Hospital of Stockholm, Sweden
[4] University Hospital of Bremen, Germany
[5] Pharma Research Preclinical, F. Hoffmann-La Roche Ltd, Basle, Switzerland
ADVENT Investigators - Source
Thrombosis and haemostasis. 1999, Vol 81, Num 4, pp 498-501 ; ref : 13 ref
- CODEN
- THHADQ
- ISSN
- 0340-6245
- Scientific domain
- Cardiology, blood circulation, phlebology; Hematology
- Publisher
- Schattauer, Stuttgart
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticoagulant Chimiothérapie Etude comparative Glycosaminoglycane Homme Héparine Inhibiteur enzyme Napsagatran Thrombin Thrombinogenèse Thrombose profonde Traitement Veine Appareil circulatoire pathologie Enzyme Hydrolases Peptidases Serine endopeptidases Vaisseau sanguin pathologie Veine pathologie
- Keyword (en)
- Anticoagulant Chemotherapy Comparative study Glycosaminoglycan Human Heparin Enzyme inhibitor Napsagatran Thrombin Thrombinogenesis Deep vein thrombosis Treatment Vein Cardiovascular disease Enzyme Hydrolases Peptidases Serine endopeptidases Vascular disease Venous disease
- Keyword (es)
- Anticoagulante Quimioterapia Estudio comparativo Glicosaminoglicano Hombre Heparina Inhibidor enzima Napsagatrán Thrombin Trombinogénesis Trombosis venosa profunda Tratamiento Vena Aparato circulatorio patología Enzima Hydrolases Peptidases Serine endopeptidases Vaso sanguíneo patología Vena patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02G Blood. Blood coagulation. Reticuloendothelial system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1737381
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1055/s-0037-1614512 
https://dx.doi.org/10.1055/s-0037-1614512
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:22:\"10.1055\/s-0037-1614512\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:200:\"Differential inhibition of thrombin activity and thrombin generation by a synthetic direct thrombin inhibitor (Napsagatran, Ro 46-6240) and unfractionated heparin in patients with deep vein thrombosis\";s:9:\"\u0000*\u0000jtitle\";s:26:\"Thrombosis and haemostasis\";s:9:\"\u0000*\u0000stitle\";s:15:\"Thromb. haemost\";s:7:\"\u0000*\u0000date\";s:4:\"1999\";s:9:\"\u0000*\u0000volume\";s:2:\"81\";s:8:\"\u0000*\u0000issue\";s:1:\"4\";s:8:\"\u0000*\u0000spage\";s:3:\"498\";s:8:\"\u0000*\u0000epage\";s:3:\"501\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0340-6245\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:10:\"BOUNAMEAUX\";s:10:\"\u0000*\u0000aufirst\";s:1:\"H\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:11:\"EHRINGER, H\";i:1;s:7:\"GAST, A\";i:2;s:10:\"HULTING, J\";i:3;s:9:\"RASCHE, H\";i:4;s:12:\"RAPOLD, H. J\";i:5;s:8:\"REBER, G\";i:6;s:13:\"TSCHOPP, T. B\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"THHADQ\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:200:\"Differential inhibition of thrombin activity and thrombin generation by a synthetic direct thrombin inhibitor (Napsagatran, Ro 46-6240) and unfractionated heparin in patients with deep vein thrombosis\";s:8:\"\u0000*\u0000place\";s:9:\"Stuttgart\";s:6:\"\u0000*\u0000pub\";s:10:\"Schattauer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:22:\"10.1055\/s-0037-1614512\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:200:\"Differential inhibition of thrombin activity and thrombin generation by a synthetic direct thrombin inhibitor (Napsagatran, Ro 46-6240) and unfractionated heparin in patients with deep vein thrombosis\";s:9:\"\u0000*\u0000jtitle\";s:26:\"Thrombosis and haemostasis\";s:9:\"\u0000*\u0000stitle\";s:15:\"Thromb. haemost\";s:7:\"\u0000*\u0000date\";s:4:\"1999\";s:9:\"\u0000*\u0000volume\";s:2:\"81\";s:8:\"\u0000*\u0000issue\";s:1:\"4\";s:8:\"\u0000*\u0000spage\";s:3:\"498\";s:8:\"\u0000*\u0000epage\";s:3:\"501\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0340-6245\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:10:\"BOUNAMEAUX\";s:10:\"\u0000*\u0000aufirst\";s:1:\"H\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:11:\"EHRINGER, H\";i:1;s:7:\"GAST, A\";i:2;s:10:\"HULTING, J\";i:3;s:9:\"RASCHE, H\";i:4;s:12:\"RAPOLD, H. J\";i:5;s:8:\"REBER, G\";i:6;s:13:\"TSCHOPP, T. B\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"THHADQ\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:200:\"Differential inhibition of thrombin activity and thrombin generation by a synthetic direct thrombin inhibitor (Napsagatran, Ro 46-6240) and unfractionated heparin in patients with deep vein thrombosis\";s:8:\"\u0000*\u0000place\";s:9:\"Stuttgart\";s:6:\"\u0000*\u0000pub\";s:10:\"Schattauer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:22:\"10.1055\/s-0037-1614512\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:22:\"10.1055\/s-0037-1614512\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:200:\"Differential inhibition of thrombin activity and thrombin generation by a synthetic direct thrombin inhibitor (Napsagatran, Ro 46-6240) and unfractionated heparin in patients with deep vein thrombosis\";s:9:\"\u0000*\u0000jtitle\";s:26:\"Thrombosis and haemostasis\";s:9:\"\u0000*\u0000stitle\";s:15:\"Thromb. haemost\";s:7:\"\u0000*\u0000date\";s:4:\"1999\";s:9:\"\u0000*\u0000volume\";s:2:\"81\";s:8:\"\u0000*\u0000issue\";s:1:\"4\";s:8:\"\u0000*\u0000spage\";s:3:\"498\";s:8:\"\u0000*\u0000epage\";s:3:\"501\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0340-6245\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:10:\"BOUNAMEAUX\";s:10:\"\u0000*\u0000aufirst\";s:1:\"H\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:11:\"EHRINGER, H\";i:1;s:7:\"GAST, A\";i:2;s:10:\"HULTING, J\";i:3;s:9:\"RASCHE, H\";i:4;s:12:\"RAPOLD, H. J\";i:5;s:8:\"REBER, G\";i:6;s:13:\"TSCHOPP, T. B\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"THHADQ\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:200:\"Differential inhibition of thrombin activity and thrombin generation by a synthetic direct thrombin inhibitor (Napsagatran, Ro 46-6240) and unfractionated heparin in patients with deep vein thrombosis\";s:8:\"\u0000*\u0000place\";s:9:\"Stuttgart\";s:6:\"\u0000*\u0000pub\";s:10:\"Schattauer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:22:\"10.1055\/s-0037-1614512\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:200:\"Differential inhibition of thrombin activity and thrombin generation by a synthetic direct thrombin inhibitor (Napsagatran, Ro 46-6240) and unfractionated heparin in patients with deep vein thrombosis\";s:9:\"\u0000*\u0000jtitle\";s:26:\"Thrombosis and haemostasis\";s:9:\"\u0000*\u0000stitle\";s:15:\"Thromb. haemost\";s:7:\"\u0000*\u0000date\";s:4:\"1999\";s:9:\"\u0000*\u0000volume\";s:2:\"81\";s:8:\"\u0000*\u0000issue\";s:1:\"4\";s:8:\"\u0000*\u0000spage\";s:3:\"498\";s:8:\"\u0000*\u0000epage\";s:3:\"501\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0340-6245\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:10:\"BOUNAMEAUX\";s:10:\"\u0000*\u0000aufirst\";s:1:\"H\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:7:{i:0;s:11:\"EHRINGER, H\";i:1;s:7:\"GAST, A\";i:2;s:10:\"HULTING, J\";i:3;s:9:\"RASCHE, H\";i:4;s:12:\"RAPOLD, H. J\";i:5;s:8:\"REBER, G\";i:6;s:13:\"TSCHOPP, T. B\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"THHADQ\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:200:\"Differential inhibition of thrombin activity and thrombin generation by a synthetic direct thrombin inhibitor (Napsagatran, Ro 46-6240) and unfractionated heparin in patients with deep vein thrombosis\";s:8:\"\u0000*\u0000place\";s:9:\"Stuttgart\";s:6:\"\u0000*\u0000pub\";s:10:\"Schattauer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
