Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl-CoA by brain microsomal long-chain fatty acyl-CoA synthetases : relevance to bipolar disorder
- Author
- BAZINET, Richard P1 ; WEIS, Margaret T2 ; RAPOPORT, Stanley I1 ; ROSENBERGER, Thad A1
[1] Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, United States
[2] Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Science Center, Amarillo, TX 79106, United States - Source
Psychopharmacologia. 2006, Vol 184, Num 1, pp 122-129, 8 p ; ref : 1 p.1/4
- CODEN
- PSYPAG
- ISSN
- 0033-3158
- Scientific domain
- Pharmacology drugs; Psychology, psychopathology, psychiatry
- Publisher
- Springer, Berlin
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Acyl-CoA synthetase Arachidonic acid Bipolar disorder Docosahexaenoic acid Kinetics Valproate
- Keyword (fr)
- Acide valproïque Anticonvulsivant Arachidonique acide Chaîne longue Cinétique Docosahexaénoïque acide Encéphale Long-chain-fatty-acid-CoA ligase Microsome Trouble bipolaire 4-Aminobutyrate transaminase Acide gras insaturé Acide gras n-3 Acide gras n-6 Acide gras polyinsaturé Carbon-sulfur ligases Enzyme Inhibiteur enzyme Ligases Lipide Système nerveux central Transaminases Transferases Trouble humeur
- Keyword (en)
- Valproic acid Anticonvulsant Arachidonic acid Long chain Kinetics Docosahexaenoic acid Encephalon Long-chain-fatty-acid-CoA ligase Microsome Bipolar disorder 4-Aminobutyrate transaminase Unsaturated fatty acid n-3 fatty acid n-6 fatty acid Polyunsaturated fatty acid Carbon-sulfur ligases Enzyme Enzyme inhibitor Ligases Lipids Central nervous system Transaminases Transferases Mood disorder
- Keyword (es)
- Acido valproico Anticonvulsivante Araquidónico ácido Cadena larga Cinética Docosahexaenóico ácido Encéfalo Long-chain-fatty-acid-CoA ligase Microsoma Trastorno bipolar 4-Aminobutyrate transaminase Acido graso no saturado Acido graso n-3 Acido graso n-6 Acido graso poliinsaturado Carbon-sulfur ligases Enzima Inhibidor enzima Ligases Lípido Sistema nervioso central Transaminases Transferases Trastorno humor
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B06 Anticonvulsants. Antiepileptics. Antiparkinson agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18C Adult and adolescent clinical studies / 002B18C07 Mood disorders / 002B18C07C Bipolar disorders
- Discipline
- Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 17417071
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00213-005-0272-4 
https://dx.doi.org/10.1007/s00213-005-0272-4
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