Thrombin and prothrombin are expressed by neurons and glial cells and accumulate in neurofibrillary tangles in Alzheimer disease brain
- Author
- ARAI, Tetsuaki1 ; MIKLOSSY, Judith1 ; KLEGERIS, Andis1 ; GUO, Jian-Ping1 ; MCGEER, Patrick L1
[1] Department of Psychiatry, Kinsmen Laboratory of Neurological Research, University of British Columbia, Vancouver, BC, Canada - Source
Journal of neuropathology and experimental neurology. 2006, Vol 65, Num 1, pp 19-25, 7 p ; ref : 26 ref
- Publisher
- Lippincott Williams & Wilkins, Hagerstown, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Aggregation Glia Immunohistochemistry Protease Proteolysis mRNA tau
- Keyword (fr)
- Agrégation Cellule gliale Démence Alzheimer Encéphale pathologie Immunohistochimie Neurone Névroglie Prothrombine Protéine tau Protéolyse Structure neurofibrillaire Système nerveux pathologie Thrombin Enzyme Hydrolases Maladie dégénérative Peptidases Serine endopeptidases Système nerveux central pathologie
- Keyword (en)
- Aggregation Glial cell Alzheimer disease Cerebral disorder Immunohistochemistry Neuron Neuroglia Prothrombin Tau protein Proteolysis Neurofibrillary tangle Nervous system diseases Thrombin Enzyme Hydrolases Degenerative disease Peptidases Serine endopeptidases Central nervous system disease
- Keyword (es)
- Agregación Célula glial Demencia Alzheimer Encéfalo patología Inmunohistoquímica Neurona Neuroglia Protrombina Proteína tau Proteolisis Estructura neurofibrilar Sistema nervioso patología Thrombin Enzima Hydrolases Enfermedad degenerativa Peptidases Serine endopeptidases Sistema nervosio central patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17C Vascular diseases and vascular malformations of the nervous system
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17423676
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1097/01.jnen.0000196133.74087.cb 
https://dx.doi.org/10.1097/01.jnen.0000196133.74087.cb
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