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Muraglitazar, a novel dual (α/γ) peroxisome proliferator-activated receptor activator, improves diabetes and other metabolic abnormalities and preserves β-cell function in db/db mice

Author
HARRITY, Thomas1 ; FARRELLY, Dennis1 ; WEI WANG2 ; HAO ZHANG2 ; FENDERSON, William3 ; CHEN, Sean2 ; DEVASTHALE, Pratik2 ; JEON, Yoon2 ; SEETHALA, Ramakrishna1 ; YANG, Wen-Pin3 ; REN, Jimmy1 ; MIN ZHOU1 ; TIEMAN, Aaron1 ; RYONO, Denis2 ; BILLER, Scott2 ; MOOKHTIAR, Kasim A1 ; WETTERAU, John1 ; GREGG, Richard1 ; CHENG, Peter T2 ; HARIHARAN, Narayanan1 ; CUIXIA CHU1 ; KUNSELMAN, Lori1 ; LIQUN GU1 ; PONTICIELLO, Randolph1 ; CAP, Michael1 ; FUCHENG QU2 ; CHUNNING SHAO2
[1] Department of Metabolic Diseases Biology, Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey, United States
[2] Department of Metabolic Diseases Chemistry, Bristol-Myers Squibb Pharmaceutical Re search Institute, Princeton, New Jersey, United States
[3] Department of Applied Genomics, Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey, United States
Source

Diabetes (New York, NY). 2006, Vol 55, Num 1, pp 240-248, 9 p ; ref : 47 ref

CODEN
DIAEAZ
ISSN
0012-1797
Scientific domain
Endocrinology; Nutrition, obesity, metabolic disorders
Publisher
American Diabetes Association, Alexandria, VA
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Activateur Animal Cellule β Diabète Récepteur PPAR-α Récepteur PPAR-γ Souris Endocrinopathie Ilot Langerhans Mammalia Pancréas endocrine Rodentia Vertebrata
Keyword (en)
Activator Animal β Cell Diabetes mellitus PPAR-α receptor PPAR-γ receptor Mouse Endocrinopathy Langerhans islet Mammalia Endocrine pancreas Rodentia Vertebrata
Keyword (es)
Activador Animal Célula β Diabetes Receptor PPAR-α Receptor PPAR-γ Ratón Endocrinopatía Isla Langerhans Mammalia Páncreas endocrino Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance

Discipline
Endocrinopathies
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17455419

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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