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Camptothecin analogs with enhanced activity against human breast cancer cells. II. Impact of the tumor pH gradient

Author
ADAMS, David J1 ; WAHL, Miriam L2 ; FLOWERS, James L1 ; SEN, Banalata1 3 ; COLVIN, Michael1 ; DEWHIRST, Mark W4 ; MANIKUMAR, Govindarajan5 ; WANI, Mansukh C5
[1] Departments of Medicine, Duke University Medical Center, 2638 Research Drive, Durham, NC 27710, United States
[2] Departments of Pathology, Duke University Medical Center, Durham, NC 27710, United States
[3] USEPA, Research Triangle Park, Durham, NC 27709, United States
[4] Departments of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, United States
[5] Research Triangle Institute, Research Triangle Park, Durham, NC 27709, United States
Source

Cancer chemotherapy and pharmacology. 2006, Vol 57, Num 2, pp 145-154, 10 p ; ref : 42 ref

CODEN
CCPHDZ
ISSN
0344-5704
Scientific domain
Medical oncology; Pharmacology drugs
Publisher
Springer, Berlin
Publication country
Germany
Document type
Article
Language
English
Author keyword
Breast cancer Drug development Camptothecin Microarray pH gradient
Keyword (fr)
Activité biologique Analogue Anticancéreux Camptothécine Carcinogenèse Cellule tumorale Gradient pH Homme Recherche développement Tumeur maligne Cancer sein Inhibiteur topoisomerase I Alcaloïde DNA topoisomerase Enzyme Glande mammaire pathologie Inhibiteur enzyme Isomerases
Keyword (en)
Biological activity Analog Antineoplastic agent Carcinogenesis Tumor cell pH gradient Human Research and development Malignant tumor Breast cancer Alkaloid DNA topoisomerase Enzyme Mammary gland diseases Enzyme inhibitor Isomerases
Keyword (es)
Actividad biológica Análogo Anticanceroso Carcinogénesis Célula tumoral Gradiente pH Hombre Investigación desarrollo Tumor maligno Cáncer pecho Alcaloide DNA topoisomerase Enzima Glándula mamaria patología Inhibidor enzima Isomerases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20E Mammary gland diseases / 002B20E02 Tumors

Discipline
Gynecology. Andrology. Obstetrics Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17489291

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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