New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis
- Author
- LIGRESTI, Alessia1 ; GRAZIA CASCIO, Maria1 ; BAKER, David2 ; MARTIN, Billy R4 ; RAZDAN, Raj K3 ; DI MARZO, Vincenzo1 ; PRYCE, Gareth2 ; KULASEGRAM, Sanjitha3 ; BELETSKAYA, Irina4 ; DE PETROCELLIS, Luciano5 ; SAHA, Bijali3 ; MAHADEVAN, Anu3 ; VISINTIN, Cristina2 ; WILEY, Jenny L4
[1] Endocannabinoid Research Group, Institute of Biomolecular Chemistry, C.N.R. Pozzuoli (Napoli), Italy
[2] Institute of Neurology, University College, London, United Kingdom
[3] Organix Inc, Woburn, MA, United States
[4] Department of Pharmacology & Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, United States
[5] Institute of Cybernetics, C.N.R. Pozzuoli (Napoli), Italy - Source
British journal of pharmacology. 2006, Vol 147, Num 1, pp 83-91, 9 p ; ref : 1 p.1/4
- CODEN
- BJPCBM
- ISSN
- 0007-1188
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- 2-arachidonoylglycerol Cannabinoid endocannabinoid membrane transport multiple sclerosis spasticity
- Keyword (fr)
- Anandamide Cannabinoïde Endocannabinoïde Hypertonie spastique Inhibiteur recapture Modèle animal Sclérose en plaques Souris Substance endogène Transport membranaire Arachidonique acide dérivé Maladie inflammatoire Mammalia Muscle strié pathologie Rodentia Système nerveux central pathologie Système nerveux pathologie Trouble neurologique Trouble tonus Vertebrata
- Keyword (en)
- Anandamide Cannabinoid Endocannabinoid Spasticity Reuptake inhibitor Animal model Multiple sclerosis Mouse Endogenous substance Membrane transport Arachidonic acid derivatives Inflammatory disease Mammalia Striated muscle disease Rodentia Central nervous system disease Nervous system diseases Neurological disorder Muscle tonus alteration Vertebrata
- Keyword (es)
- Anandamide Canabinoide Endocanabinoide Hipertonia espástica Inhibidor recaptura Modelo animal Esclerosis en placa Ratón Substancia endógena Transporte membranal Araquidónico ácido derivado Enfermedad inflamatoria Mammalia Músculo estriado patología Rodentia Sistema nervosio central patología Sistema nervioso patología Trastorno neurológico Trastorno tono muscular Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17A Nervous system (semeiology, syndromes) / 002B17A01 Nervous system as a whole
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17F Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis
- Discipline
- General pharmacology Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17675355
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.bjp.0706418 
https://dx.doi.org/10.1038/sj.bjp.0706418
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