Designed divergent evolution of enzyme function
- Auteur
- YOSHIKUNI, Yasuo1 2 ; FERRIN, Thomas E1 3 ; KEASLING, Jay D1 2 4 5
[1] UCSF/UCB Joint Graduate Group in Bioengineering, University of California at Berkeley, Berkeley, California 94720, United States
[2] Synthetic Biology Department, Physical Bioscience Division, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States
[3] Department of Pharmaceutical Chemistry and Biopharmaceutical Sciences, University of California at San Francisco, San Francisco, California 94143, United States
[4] Department of Chemical Engineering, University of California at Berkeley, Berkeley, California 94720, United States
[5] California Institute for Quantitative Biomedical Research (QB3), University of California at Berkeley, Berkeley, California 94720, United States - Source
Nature (London). 2006, Vol 440, Num 7087, pp 1078-1082, 5 p ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Domaine scientifique
- Multidisciplinary
- Editeur
- Nature Publishing, London
- Pays de publication
- United Kingdom
- Type de document
- Article
- Langue
- English
- Mot clé (fr)
- Conception Enzyme Evolution moléculaire dirigée Modèle mathématique Site actif Site fixation Substitution
- Mot clé (en)
- Design Enzyme Directed molecular evolution Mathematical model Active site Binding site Substitution
- Mot clé (es)
- Diseño Enzima Evolución molecular dirigida Modelo matemático Lugar activo Sitio fijación Substitución
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002A Sciences biologiques fondamentales et appliquees. Psychologie / 002A31 Biotechnologie / 002A31C Méthodes. Procédés. Technologies / 002A31C04 Génie protéique
- Discipline
- Biotechnology
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 17700494
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature04607 
https://dx.doi.org/10.1038/nature04607
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