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G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid leukemia cells is p21 dependent and MLL-AF9 independent

Author
TONELLI, R1 ; SARTINI, R1 ; CAPRANICO, G7 ; KHOBTA, A7 ; CAMPANINI, R2 ; PAOLUCCI, P8 ; MINUCCI, S3 9 ; PESSION, A1 ; FRONZA, R1 ; FRECCERO, F1 ; FRANZONI, M1 ; DONGIOVANNI, D2 ; BALLARINI, M3 ; FERRARI, S4 ; D'APOLITO, M5 ; DI COLA, G6
[1] Department of Pediatrics, University of Bologna, Bologna, Italy
[2] Department of Physics, University of Bologna, Bologna, Italy
[3] Department of Experimental Oncology, European Institute of Oncology, Milan, Italy
[4] Division of Medical Genetics, S. Orsola Hospital, Bologna, Italy
[5] Servizio di Genetica Medica, IRCCS-Ospedale CSS, San Giovanni Rotondo, Italy
[6] Biotech Biotechnologies Laboratory s.r.l, Parma, Italy
[7] Department of Biochemistry, University of Bologna, Bologna, Italy
[8] Department of Pediatrics, University of Modena, Modena, Italy
[9] Department of Biomolecular Sciences and Biotechnology, University of Milan, Milan, Italy
Source

Leukemia. 2006, Vol 20, Num 7, pp 1307-1310, 4 p ; ref : 8 ref

CODEN
LEUKED
ISSN
0887-6924
Scientific domain
Medical oncology; Hematology
Publisher
Nature Publishing, London
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Aigu Apoptose Cycle cellulaire Gène CDKN1A Gène hybride Gène suppresseur tumeur Homme Hématologie Inhibiteur histone deacetylase Leucémie myéloblastique Mort cellulaire Phase G1 Gène AF9 Gène MLL Hémopathie maligne
Keyword (en)
Acute Apoptosis Cell cycle CDKN1A Gene Hybrid gene Tumor suppressor gene Human Hematology Histone deacetylase inhibitor Acute myelocytic leukemia Cell death G1 Phase AF9 gene Malignant hemopathy
Keyword (es)
Agudo Apoptosis Ciclo celular Gen CDKN1A Gen híbrido Gen supresor tumor Hombre Hematología Inhibidor histone deacetylase Leucemia mieloblástica Muerte celular Fase G1 Hemopatía maligna
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis

Discipline
Blood diseases
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17905393

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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