The immunologically active site of prothymosin α is located at the carboxy-terminus of the polypeptide. Evaluation of its in vitro effects in cancer patients
- Author
- SKOPELITI, Margarita1 ; VOUTSAS, Ioannis F1 ; TSITSILONIS, Ourania E1 ; KLIMENTZOU, Persefoni2 ; TSIATAS, Marinos L3 ; BECK, Alexander4 ; BAMIAS, Aristotelis3 ; MORAKI, Maria5 ; LIVANIOU, Evangelia2 ; NEAGU, Monica6 ; VOELTER, Wolfgang7
[1] Department of Animal and Human Physiology, Faculty of Biology, University of Athens, Panepistimiopolis, 15784, Ilissia, Athens, Greece
[2] Institute of RRP, NCSR Demokritos, Aghia Paraskevi, Athens, Greece
[3] Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, University of Athens, Athens, Greece
[4] Central Laboratory, Department of Internal Medicine IV, University Clinic of Tuebingen, Tuebingen, Germany
[5] Blood Transfusion Unit, St. Savas Cancer Hospital, Athens, Greece
[6] Immunology Laboratory, Victor Babes National Research Institute, Bucharest, Romania
[7] Biochemistry Institute, University of Tuebingen, Tuebingen, Germany - Source
Cancer immunology and immunotherapy. 2006, Vol 55, Num 10, pp 1247-1257, 11 p ; ref : 48 ref
- CODEN
- CIIMDN
- ISSN
- 0340-7004
- Scientific domain
- Biochemistry, molecular biology, biophysics; Medical oncology; Immunology, immunopathology, allergology
- Publisher
- Springer, Berlin
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Anticancer activity Cell proliferation Cytotoxicity Immune responses Prothymosin α fragmentation
- Keyword (fr)
- Activité biologique Anticancéreux Cytotoxicité Evaluation Fragmentation Homme Immunothérapie In vitro Multiplication cellulaire Polypeptide Réponse immune Site actif Séquence C terminale Traitement Tumeur maligne
- Keyword (en)
- Biological activity Antineoplastic agent Cytotoxicity Evaluation Fragmentation Human Immunotherapy In vitro Cell proliferation Polypeptide Immune response Active site C terminal-Sequence Treatment Malignant tumor
- Keyword (es)
- Actividad biológica Anticanceroso Citotoxicidad Evaluación Fragmentación Hombre Inmunoterapia In vitro Multiplicación celular Polipéptido Respuesta inmune Lugar activo Secuencia C terminal Tratamiento Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R03 Immunotherapy
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17962323
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00262-005-0108-4 
https://dx.doi.org/10.1007/s00262-005-0108-4
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