Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins : Their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations
- Author
- ANDRE, Sabine1 ; ZHICHAO PEI2 ; SIEBERT, Hans-Christian1 ; RAMSTRÖM, Olof2 ; GABIUS, Hans-Joachim1
[1] Institut für Physiologist-he Chemie, Tierärztliche Fakultät, Ludwig -Maximilians-Universität München, Veterinärstr. 13, 80539 München, Germany
[2] KTH-Royal Institute of Technology, Department of Chemistry, Teknikringen 30, 10044 Stockholm, Sweden - Source
Bioorganic & medicinal chemistry. 2006, Vol 14, Num 18, pp 6314-6326, 13 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Agglutinin Combinatorial chemistry Drug design Dynamic chemistry Galectin Glycosyldisulfide Neoglycoprotein
- Keyword (fr)
- Activité biologique Agglutinine Aldose Aminoglycoside Analyse conformationnelle Cellule tumorale Chimie combinatoire Chimiothèque Disulfure organique Fucose Galactose Galectine Glycane Glycoprotéine Homme In vitro Inhibiteur Lactose Lectine Ligand Mimétique Modélisation Méthode dynamique moléculaire Phase solide Plante Polyoside Protéine Ricine Résistance hydrolyse Thioglycoside Thiol Trouble fonctionnel
- Keyword (en)
- Biological activity Agglutinin Aldose Aminoglycoside Conformational analysis Tumor cell Combinatorial chemistry Chemical compound library Organic disulfide Fucose Galactose Galectin Glycan Glycoprotein Human In vitro Inhibitor Lactose Lectin Ligand Mimetic Modeling Molecular dynamics method Solid phase Plant Polysaccharide Protein Ricin Hydrolysis resistance Thioglycoside Thiol Dysfunction
- Keyword (es)
- Actividad biológica Aglutinina Aldosa Aminoglicósido Análisis conformacional Célula tumoral Química combinatoria Quimioteca Disulfuro orgánico Fucosa Galactosa Galectina Glicano Glicoproteína Hombre In vitro Inhibidor Lactosa Lectina Ligando Mimético Modelización Método dinámico molecular Fase sólida Planta Poliósido Proteína Ricina Resistencia hidrólisis Tioglicósido Tiol Trastorno funcional
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18059759
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1016/j.bmc.2006.05.045 
https://dx.doi.org/10.1016/j.bmc.2006.05.045
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1016\/j.bmc.2006.05.045\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:226:\"Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins : Their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations\";s:9:\"\u0000*\u0000jtitle\";s:32:\"Bioorganic & medicinal chemistry\";s:9:\"\u0000*\u0000stitle\";s:17:\"Bioorg. med. chem\";s:7:\"\u0000*\u0000date\";s:4:\"2006\";s:9:\"\u0000*\u0000volume\";s:2:\"14\";s:8:\"\u0000*\u0000issue\";s:2:\"18\";s:8:\"\u0000*\u0000spage\";s:4:\"6314\";s:8:\"\u0000*\u0000epage\";s:4:\"6326\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0968-0896\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"ANDRE\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Sabine\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:4:{i:0;s:11:\"ZHICHAO PEI\";i:1;s:23:\"SIEBERT, Hans-Christian\";i:2;s:15:\"RAMSTR\u00d6M, Olof\";i:3;s:20:\"GABIUS, Hans-Joachim\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:226:\"Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins : Their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations\";s:8:\"\u0000*\u0000place\";s:6:\"Oxford\";s:6:\"\u0000*\u0000pub\";s:16:\"Elsevier Science\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"13\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1016\/j.bmc.2006.05.045\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:226:\"Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins : Their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations\";s:9:\"\u0000*\u0000jtitle\";s:32:\"Bioorganic & medicinal chemistry\";s:9:\"\u0000*\u0000stitle\";s:17:\"Bioorg. med. chem\";s:7:\"\u0000*\u0000date\";s:4:\"2006\";s:9:\"\u0000*\u0000volume\";s:2:\"14\";s:8:\"\u0000*\u0000issue\";s:2:\"18\";s:8:\"\u0000*\u0000spage\";s:4:\"6314\";s:8:\"\u0000*\u0000epage\";s:4:\"6326\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0968-0896\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"ANDRE\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Sabine\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:4:{i:0;s:11:\"ZHICHAO PEI\";i:1;s:23:\"SIEBERT, Hans-Christian\";i:2;s:15:\"RAMSTR\u00d6M, Olof\";i:3;s:20:\"GABIUS, Hans-Joachim\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:226:\"Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins : Their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations\";s:8:\"\u0000*\u0000place\";s:6:\"Oxford\";s:6:\"\u0000*\u0000pub\";s:16:\"Elsevier Science\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"13\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:25:\"10.1016\/j.bmc.2006.05.045\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1016\/j.bmc.2006.05.045\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:226:\"Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins : Their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations\";s:9:\"\u0000*\u0000jtitle\";s:32:\"Bioorganic & medicinal chemistry\";s:9:\"\u0000*\u0000stitle\";s:17:\"Bioorg. med. chem\";s:7:\"\u0000*\u0000date\";s:4:\"2006\";s:9:\"\u0000*\u0000volume\";s:2:\"14\";s:8:\"\u0000*\u0000issue\";s:2:\"18\";s:8:\"\u0000*\u0000spage\";s:4:\"6314\";s:8:\"\u0000*\u0000epage\";s:4:\"6326\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0968-0896\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"ANDRE\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Sabine\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:4:{i:0;s:11:\"ZHICHAO PEI\";i:1;s:23:\"SIEBERT, Hans-Christian\";i:2;s:15:\"RAMSTR\u00d6M, Olof\";i:3;s:20:\"GABIUS, Hans-Joachim\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:226:\"Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins : Their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations\";s:8:\"\u0000*\u0000place\";s:6:\"Oxford\";s:6:\"\u0000*\u0000pub\";s:16:\"Elsevier Science\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"13\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:11:\"BaseOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1016\/j.bmc.2006.05.045\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:226:\"Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins : Their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations\";s:9:\"\u0000*\u0000jtitle\";s:32:\"Bioorganic & medicinal chemistry\";s:9:\"\u0000*\u0000stitle\";s:17:\"Bioorg. med. chem\";s:7:\"\u0000*\u0000date\";s:4:\"2006\";s:9:\"\u0000*\u0000volume\";s:2:\"14\";s:8:\"\u0000*\u0000issue\";s:2:\"18\";s:8:\"\u0000*\u0000spage\";s:4:\"6314\";s:8:\"\u0000*\u0000epage\";s:4:\"6326\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0968-0896\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"ANDRE\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Sabine\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:4:{i:0;s:11:\"ZHICHAO PEI\";i:1;s:23:\"SIEBERT, Hans-Christian\";i:2;s:15:\"RAMSTR\u00d6M, Olof\";i:3;s:20:\"GABIUS, Hans-Joachim\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:226:\"Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins : Their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations\";s:8:\"\u0000*\u0000place\";s:6:\"Oxford\";s:6:\"\u0000*\u0000pub\";s:16:\"Elsevier Science\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"13\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Base Search access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1016\/j.bmc.2006.05.045\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:226:\"Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins : Their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations\";s:9:\"\u0000*\u0000jtitle\";s:32:\"Bioorganic & medicinal chemistry\";s:9:\"\u0000*\u0000stitle\";s:17:\"Bioorg. med. chem\";s:7:\"\u0000*\u0000date\";s:4:\"2006\";s:9:\"\u0000*\u0000volume\";s:2:\"14\";s:8:\"\u0000*\u0000issue\";s:2:\"18\";s:8:\"\u0000*\u0000spage\";s:4:\"6314\";s:8:\"\u0000*\u0000epage\";s:4:\"6326\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0968-0896\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"ANDRE\";s:10:\"\u0000*\u0000aufirst\";s:6:\"Sabine\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:4:{i:0;s:11:\"ZHICHAO PEI\";i:1;s:23:\"SIEBERT, Hans-Christian\";i:2;s:15:\"RAMSTR\u00d6M, Olof\";i:3;s:20:\"GABIUS, Hans-Joachim\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:226:\"Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins : Their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations\";s:8:\"\u0000*\u0000place\";s:6:\"Oxford\";s:6:\"\u0000*\u0000pub\";s:16:\"Elsevier Science\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"13\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
