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Plaque- associated overexpression of insulin-degrading enzyme in the cerebral cortex of aged transgenic Tg2576 mice with Alzheimer pathology

Author
LEAL, Maria C1 ; DORFMAN, Veronica B1 ; GAMBA, Agata Fernandez1 ; FRANGIONE, Blas2 3 ; WISNIEWSKI, Thomas2 3 4 ; CASTANO, Eduardo M1 3 ; SIGURDSSON, Einar M2 ; MORELLI, Laura1
[1] Fundación Instituto Leloir Instituto de Investigaciones Bioquímicas de Buenos Aires (CONICET), Ciudad de Buenos Aires, Argentina
[2] Department of Psychiatry, New York University School of Medicine, New York, NY, United States
[3] Department of Neurology, New York University School of Medicine, New York, NY, United States
[4] Department of Pathology, New York University School of Medicine, New York, NY, United States
Source

Journal of neuropathology and experimental neurology. 2006, Vol 65, Num 10, pp 976-987, 12 p ; ref : 63 ref

CODEN
JNENAD
ISSN
0022-3069
Scientific domain
Neurology
Publisher
Lippincott Williams & Wilkins, Hagerstown, MD
Publication country
United States
Document type
Article
Language
English
Author keyword
Alzheimer disease Amyloid β Astrocytes Inflammation Insulin-degrading enzyme MAPK cascades Microglia Transgenic mice
Keyword (fr)
Anatomopathologie Animal transgénique Astrocyte Cortex cérébral Démence Alzheimer Enzyme Inflammation Insuline Microglie Mitogen-activated protein kinase Protéine amyloïde β Souris Surexpression génique Système nerveux pathologie Encéphale pathologie Hormone pancréatique Maladie dégénérative Mammalia Névroglie Rodentia Système nerveux central pathologie Système nerveux central Vertebrata
Keyword (en)
Anatomic pathology Transgenic animal Astrocyte Cerebral cortex Alzheimer disease Enzyme Inflammation Insulin Microglia Mitogen-activated protein kinase β Amyloid protein Mouse Gene overexpression Nervous system diseases Cerebral disorder Pancreatic hormone Degenerative disease Mammalia Neuroglia Rodentia Central nervous system disease Central nervous system Vertebrata
Keyword (es)
Anatomía patológica Animal transgénico Astrocito Corteza cerebral Demencia Alzheimer Enzima Inflamación Insulina Microglia Mitogen-activated protein kinase Proteína amiloide β Ratón Sobreexpressión genética Sistema nervioso patología Encéfalo patología Hormona pancreática Enfermedad degenerativa Mammalia Neuroglia Rodentia Sistema nervosio central patología Sistema nervioso central Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05C Viral diseases / 002B05C02 Human viral diseases / 002B05C02A Viral diseases of the nervous system

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05D Mycoses / 002B05D02 Human mycoses / 002B05D02I Mycoses of the nervous system

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology

Discipline
Infectious pathology Neurology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18176391

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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