Significantly improved PCR-based clonality testing in B-cell malignancies by use of multiple immunoglobulin gene targets. Report of the BIOMED-2 concerted action BHM4-CT98-3936
- Author
- EVANS, P. A. S1 ; POTT, Ch2 ; SCHUURING, E9 ; SPAARJAREN, M8 ; BOONE, E10 ; GONZALEZ, D11 ; MARTINEZ, B12 ; VILLUENDAS, R7 ; GAMEIRO, P13 ; DISS, T. C14 ; MILLS, K15 ; MORGAN, G. J1 ; GROENEN, P. J. T. A3 ; CARTER, G. I16 ; MILNER, B. J17 ; PEARSON, D18 ; HUMMEL, M19 ; JUNG, W20 ; OTT, M21 ; CANIONI, D22 ; BELDJORD, K23 ; BASTARD, C24 ; DELFAU-LARUE, M. H25 ; SALLES, G4 ; VAN DONGEN, J. J. M; MOLINA, T. J; CABEYADAS, J; DAVI, F5 ; BERGER, F6 ; GARCIA, J. F7 ; VAN KRIEKEN, J. H. J. M3 ; PALS, S8 ; KLUIN, Ph9
[1] Haematological Malignancy Diagnostic Service, The General Infirmary at Leeds, Leeds, United Kingdom
[2] II. Medical Department, University Hospital Schleswig-Holstein, Kiel, Germany
[3] Department of Pathology, Radboud University, Nijmegen Medical Center, Nijmegen, Netherlands
[4] Department of Haematology, Centre Hospitalier Lyon-Sud, Lyon, France
[5] Department of Haematology, Hopital Pitié-Salpétière, Paris, France
[6] Department of Pathology, Centre Hospitalier Lyon-Sud, Lyon, France
[7] Molecular Pathology Program, CNIO, Madrid, Spain
[8] Department of Pathology, Academic Medical Center, Amsterdam, Netherlands
[9] Department of Pathology, University Medical Center Groningen, Groningen, Netherlands
[10] Laboratory for Molecular Diagnostics, H. Hartziekenhuis, Roeselare, Belgium
[11] Department of Hematology, Hospital Universitario de Salamanca, Salamanca, Spain
[12] Department of Human Genetics, Centro Nacional de Investigaciones Oncológicas, Madrid, Spain
[13] Lab. Biologia Molecular, Instituto Português de Oncologia, Lisbon, Portugal
[14] Department of Histopathology, Royal Free and UCL Medical School, London, United Kingdom
[15] Department of Haematology, University of Wales College of Medicine, Cardiff, United Kingdom
[16] Molecular Diagnostics, Nottingham City Hospital NHS Trust, Nottingham, United Kingdom
[17] Department of Medicine and Therapeutics, University of Aberdeen, Aberdeen, United Kingdom
[18] Department of Pathology, Cambridge University, Addenbrooke's NHS Trust Hospital, Cambridge, United Kingdom
[19] Institut für Pathologie, Campus Benjamin Franklin, Charité -Universitätsmedizin Berlin, Berlin, Germany
[20] Department of Internal Medicine, Georg-August-University of Goettingen, Goettingen, Germany
[21] Department of Pathology, Luitpoldkrankenhaus, Würzburg, Germany
[22] Service d'Anatomie Pathologique, Hôpital Necker-Enfants Malades, Paris, France
[23] Laboratoire d'Hematologie, Hôpital Necker-Enfants Malades, Paris, France
[24] Laboratoire de Genetique Oncologique, Centre Henri Becquerel, Rouen, France
[25] Service d'lmmunologie Biologique, Groupe Hospitalier Henri Mondor, AlbertChenevier AP-HP, Creteil, France - Source
Leukemia. 2007, Vol 21, Num 2, pp 207-214, 8 p ; ref : 40 ref
- CODEN
- LEUKED
- ISSN
- 0887-6924
- Scientific domain
- Medical oncology; Hematology
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- B-cell malignancies BIOMED-2 PCR TCR rearrangements clonality lg rearrangements
- Keyword (fr)
- Ciblage Clonalité Dépistage Gène Génétique Hématologie Immunoglobuline Lymphocyte B Malignité Réaction chaîne polymérase Réarrangement génique Récepteur cellule T Tumeur maligne Biologie moléculaire
- Keyword (en)
- Targeting Clonality Medical screening Gene Genetics Hematology Immunoglobulins B-Lymphocyte Malignancy Polymerase chain reaction Gene rearrangement T cell receptor Malignant tumor Molecular biology
- Keyword (es)
- Blancado Clonalidad Descubrimiento Gen Genética Hematología Inmunoglobulina Linfocito B Malignidad Reacción cadena polimerasa Redisposición génica Receptor célula T Tumor maligno Biología molecular
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases
- Discipline
- Blood diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18534502
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.leu.2404479 
https://dx.doi.org/10.1038/sj.leu.2404479
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