TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
- Author
- GACK, Michaela U1 2 ; SHIN, Young C1 ; JUNG, Jae U1 ; JOO, Chul-Hyun1 3 ; URANO, Tomohiko4 5 ; CHENGYU LIANG1 ; LIJUN SUN6 ; TAKEUCHI, Osamu7 ; AKIRA, Shizuo7 ; ZHIJIAN CHEN6 ; INOUE, Satoshi4 5
[1] Department of Microbiology and Molecular Genetics and Tumor Virology Division, New England Primate Research Center, Harvard Medical School, 1 Pine Hill Drive, Southborough, Massachusetts 01772, United States
[2] Institute for Clinical and Molecular Virology, Friedrich-Alexander University Erlangen-Nuremberg, 91054 Erlangen, Germany
[3] Department of Microbiology, University of Ulsan College of Medicine, Seoul 138-736, Korea, Republic of
[4] Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-8655, Japan
[5] Research Center for Genomic Medicine, Saitama Medical School, Saitama 350-124-2, Japan
[6] Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9148, United States
[7] Department of Host Defense, Japan Science and Technology Agency, Osaka 565-0871, Japan - Source
Nature (London). 2007, Vol 446, Num 7138, pp 916-920, 5 p ; ref : 21 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Antiviral Doigt Immunité naturelle Récepteur biologique Transduction signal Ubiquitin-protein ligase Virus à ARN Gène DDX58 Gène TRIM25 Carbon-nitrogen ligases Enzyme Ligases
- Keyword (en)
- Biological activity Antiviral Finger Natural immunity Biological receptor Signal transduction Ubiquitin-protein ligase RNA virus Carbon-nitrogen ligases Enzyme Ligases
- Keyword (es)
- Actividad biológica Antiviral Dedo Inmunidad natural Receptor biológico Transducción señal Ubiquitin-protein ligase Virus con RNA Carbon-nitrogen ligases Enzima Ligases
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A06 Fundamental immunology / 002A06C Immunobiology / 002A06C06 Genetics of the immune response
- Discipline
- Fundamental immunology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18673307
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature05732 
https://dx.doi.org/10.1038/nature05732
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