Concurrent determination of ezetimibe and its phase-I and II metabolites by HPLC with UV detection : Quantitative application to various in vitro metabolic stability studies and for qualitative estimation in bile
- Author
- SHAIK JAFAR SADIK BASHA1 ; SHAIK ABDUL NAVEED1 ; SRINIVAS, Nuggehally R1 3 ; NIRBHAY KUMAR TIWARI1 ; SHASHIKUMAR, Dhanya1 ; MUZEEB, Syed1 ; THAMMERA RANJITH KUMAR1 ; NYAVANANDI VIJAY KUMAR2 ; NADIPALLI PRABHAKAR RAO2 ; SRINIVAS, Nanduri2 ; MULLANGI, Ramesh1
[1] Drug Metabolism and Pharmacokinetics, Discovery Research, Dr. Reddy's Laboratories Ltd, Miyapur, Hyderabad 500 049, India
[2] Discovery Chemistry, Discovery Research, Dr. Reddy's Laboratories Ltd, Miyapur, Hyderabad 500 049, India
[3] Drug Development, Discovery Research, Dr. Reddy's Laboratories Ltd, Miyapur, Hyderabad 500 049, India - Source
Journal of chromatography. B. 2007, Vol 853, Num 1-2, pp 88-96, 9 p ; ref : 18 ref
- ISSN
- 1570-0232
- Scientific domain
- Medical laboratory techniques; Pharmacology drugs
- Publisher
- Elsevier Science, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Ezetimibe glucuronide Ezetimibe ketone glucuronide Ezetimibe ketone Ezetimibe HPLC Metabolism
- Keyword (fr)
- Analyse quantitative Bile Chromatographie HPLC Cétone Détecteur UV Détermination Ezétimibe Glucuroconjugué Hypolipémiant In vitro Métabolisme Métabolite Stabilité LC UV Pharmacocinétique Propriété physicochimique
- Keyword (en)
- Quantitative analysis Bile HPLC chromatography Ketone Ultraviolet detector Determination Ezetimibe Glucuroconjugate Antilipemic agent In vitro Metabolism Metabolite Stability Pharmacokinetics Physicochemical properties
- Keyword (es)
- Análisis cuantitativo Bilis Cromatografía HPLC Cetona Detector UV Determinación Ezetimiba Glucuroconjugado Hipolipemiante In vitro Metabolismo Metabolito Estabilidad Farmacocinética Propiedad fisicoquímica
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis
- Discipline
- Analytical, structural and metabolic biochemistry General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18847085
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.jchromb.2007.02.053 
https://dx.doi.org/10.1016/j.jchromb.2007.02.053
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