Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants
- Author
- AYODO, George1 2 ; PRICE, Alkes L1 ; KEINAN, Alon1 ; AJWANG, Arthur2 ; OTIENO, Michael F2 ; ORAGO, Alloys S. S2 ; PATTERSON, Nick1 ; REICH, David1
[1] Department of Genetics, Harvard Medical School, and Broad Institute of Harvard and MIT, Boston, United States
[2] Department of Pre-Clinical Sciences, Kenyatta University, Nairobi, United States - Source
American journal of human genetics. 2007, Vol 81, Num 2, pp 234-242, 9 p ; ref : 44 ref
- Publisher
- University of Chicago Press, Chicago, IL
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Association Augmentation Génétique Homme Paludisme Puissance Résistance Sélection naturelle Variant Infection Parasitose Protozoose
- Keyword (en)
- Association Increase Genetics Human Malaria Power Resistance Natural selection Variant Infection Parasitosis Protozoal disease
- Keyword (es)
- Asociación Aumentación Genética Hombre Paludismo Potencia Resistencia Selección natural Variante Infección Parasitosis Protozoosis
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05E Parasitic diseases / 002B05E02 Protozoal diseases / 002B05E02B Human protozoal diseases / 002B05E02B4 Malaria
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B23 Medical genetics / 002B23A General aspects. Genetic counseling
- Discipline
- Eukaryotes genetics. Biological and molecular evolution Infectious pathology Medical genetics Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18973904
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1086/519221 
https://dx.doi.org/10.1086/519221
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