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The epigenetic code replication machinery, ECREM : A promising drugable target of the epigenetic cell memory

Author
BRONNER, Christian1 ; CHATAIGNEAU, Thierry1 ; SCHINI-KERTH, Valérie B1 ; LANDRY, Yves1
[1] CNRS UMR 7175, Département de Pharmacologie et Pharmacochimie des Interactions cellulaires et moléculaires, Faculté de Pharmacie, 74 route du Rhin, B.P. 60024, 67401 Illkirch, France
Source

Current medicinal chemistry. 2007, Vol 14, Num 25, pp 2629-2641, 13 p ; ref : 142 ref

ISSN
0929-8673
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Bentham Science, Schiphol
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Cancer DNA methyltransferase drug epigenetic histone acetyltransferases histone code histone deacetylases inhibitors neuro-degenerative disorders sirtuins therapy
Keyword (fr)
Anticancéreux DNA Epigénétique Histone acetyltransferase Histone Hydrolases Inhibiteur enzyme Maladie dégénérative Maladie inflammatoire Methyltransferases Modification posttraductionnelle Mécanisme Médicament ciblé Méthylation Protéine nucléaire Recherche et développement Réplication Traitement Trouble métabolique Vieillissement Histone deacetylase Acyltransferases Enzyme Transferases
Keyword (en)
Antineoplastic agent DNA Epigenetics Histone acetyltransferase Histone Hydrolases Enzyme inhibitor Degenerative disease Inflammatory disease Methyltransferases Posttranslational modification Mechanism Targeted drug Methylation Nuclear protein Research and development Replication Treatment Metabolic disorder Ageing Acyltransferases Enzyme Transferases
Keyword (es)
Anticanceroso DNA Epigenética Histone acetyltransferase Histona Hydrolases Inhibidor enzima Enfermedad degenerativa Enfermedad inflamatoria Methyltransferases Modificación postraduccional Mecanismo Medicamento dirigido Metilación Proteína nuclearia Investigación desarrollo Replicación Tratamiento Trastorno metabolismo Envejecimiento Acyltransferases Enzima Transferases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
19148603

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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