Multiple factors contribute to the toxicity of the aromatic retinoid TTNPB (Ro 13-7410) : Interactions with the retinoic acid receptors
- Author
- PIGNATELLO, M. A1 2 ; KAUFFMAN, F. C1 ; LEVIN, A. A3
[1] Laboratory of Cellular and Biochemical Toxicology, Rutgers University, Piscataway, New Jersey 08854, United States
[2] Department of Toxicology and Pathology, Hoffmann-LaRoche Inc., Nutley, New Jersey 07110, United States
[3] ISIS Pharmaceuticals, Carlsbad, California 92008, United States - Source
Toxicology and applied pharmacology. 1999, Vol 159, Num 2, pp 109-116 ; ref : 1 p.1/4
- CODEN
- TXAPA9
- ISSN
- 0041-008X
- Scientific domain
- Pharmacology drugs; Toxicology
- Publisher
- Elsevier, San Diego, CA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Etude comparative Fixation biologique In vitro Mécanisme action Protéine liaison Relation métabolisme toxicité Récepteur biologique Rétinoïde Rétinoïque acide Toxicité Tératogène Lignée JEG3 Protéine CRABP RO 13 7410 Récepteur rétinoique acide RAR
- Keyword (en)
- Comparative study Biological fixation In vitro Mechanism of action Binding protein Metabolism toxicity relation Biological receptor Retinoid Retinoic acid Toxicity Teratogen
- Keyword (es)
- Estudio comparativo Fijación biológica In vitro Mecanismo acción Proteína enlace Relación metabolismo toxicidad Receptor biológico Retinoide Retinoico ácido Toxicidad Teratogeno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02U Drug toxicity and drugs side effects treatment / 002B02U10 Miscellaneous (drug allergy, mutagens, teratogens...)
- Discipline
- Drugs toxicity and drug intoxications Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1997227
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1006/taap.1999.8726 
https://dx.doi.org/10.1006/taap.1999.8726
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