Single Injection of a Sustained-release Prostacyclin Analog Improves Pulmonary Hypertension in Rats
- Author
- OBATA, Hiroaki1 2 ; SAKAI, Yoshiki3 ; OHNISHI, Shunsuke1 ; TAKESHITA, Satoshi4 ; MORI, Hidezo5 ; KODAMA, Makoto2 ; KANGAWA, Kenji6 ; AIZAWA, Yoshifusa2 ; NAGAYA, Noritoshi1 4
[1] Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center Research Institute, Osaka, Japan
[2] Division of Cardiology, Niigata University Graduate School of Medical and Dental Science, Niigata, Japan
[3] Ono Pharmaceutical Co. Ltd., Research Headquarters, Osaka, Japan
[4] Department of Internal Medicine, National Cardiovascular Center, Osaka, Japan
[5] Department of Cardiac Physiology, National Cardiovascular Center Research Institute, Osaka, Japan
[6] Department of Biochemistry, National Cardiovascular Center Research Institute, Osaka, Japan - Source
American journal of respiratory and critical care medicine. 2008, Vol 177, Num 2, pp 195-201, 7 p ; ref : 38 ref
- ISSN
- 1073-449X
- Scientific domain
- Pneumology
- Publisher
- American Lung Association, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- extracellular signal regulated kinase poly(lactic-co- glycolic acid) prostacyclin analog pulmonary hypertension sustained- release preparation
- Keyword (fr)
- Acide glycolique Acide lactique Animal Dose unique Forme libération contrôlée Hypertension artérielle pulmonaire Prostaglandine I2 Rat Réanimation Soin intensif Hydroxyacide Mammalia Pathologie de l'appareil circulatoire Pathologie de l'appareil respiratoire Rodentia Vertebrata
- Keyword (en)
- Glycolic acid Lactic acid Animal Single dose Controlled release form Pulmonary hypertension Prostaglandin I2 Rat Resuscitation Intensive care Hydroxyacid Mammalia Cardiovascular disease Respiratory disease Rodentia Vertebrata
- Keyword (es)
- Glicolico ácido Láctico ácido Animal Dosis única Forma liberación controlada Hipertensión arterial pulmonar Prostaglandina I2 Rata Reanimación Cuidado intensivo Hidroxiácido Mammalia Aparato circulatorio patología Aparato respiratorio patología Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11C Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12B Blood and lymphatic vessels / 002B12B05 Arterial hypertension. Arterial hypotension / 002B12B05B Clinical manifestations. Epidemiology. Investigative techniques. Etiology
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B27 Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy / 002B27B Intensive care medicine
- Discipline
- Anaesthesia. Reanimation. Transfusion. Cell therapy and gene therapy Cardiology. Circulatory system Pulmonology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 19977745
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1164/rccm.200703-349OC 
https://dx.doi.org/10.1164/rccm.200703-349OC
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1164\/rccm.200703-349OC\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:99:\"Single Injection of a Sustained-release Prostacyclin Analog Improves Pulmonary Hypertension in Rats\";s:9:\"\u0000*\u0000jtitle\";s:58:\"American journal of respiratory and critical care medicine\";s:9:\"\u0000*\u0000stitle\";s:29:\"Am. j. respir. crit. care med\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:3:\"177\";s:8:\"\u0000*\u0000issue\";s:1:\"2\";s:8:\"\u0000*\u0000spage\";s:3:\"195\";s:8:\"\u0000*\u0000epage\";s:3:\"201\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1073-449X\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"OBATA\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Hiroaki\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:14:\"SAKAI, Yoshiki\";i:1;s:17:\"OHNISHI, Shunsuke\";i:2;s:18:\"TAKESHITA, Satoshi\";i:3;s:12:\"MORI, Hidezo\";i:4;s:14:\"KODAMA, Makoto\";i:5;s:14:\"KANGAWA, Kenji\";i:6;s:17:\"AIZAWA, Yoshifusa\";i:7;s:17:\"NAGAYA, Noritoshi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:99:\"Single Injection of a Sustained-release Prostacyclin Analog Improves Pulmonary Hypertension in Rats\";s:8:\"\u0000*\u0000place\";s:12:\"New York, NY\";s:6:\"\u0000*\u0000pub\";s:25:\"American Lung Association\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"7\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1164\/rccm.200703-349OC\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:99:\"Single Injection of a Sustained-release Prostacyclin Analog Improves Pulmonary Hypertension in Rats\";s:9:\"\u0000*\u0000jtitle\";s:58:\"American journal of respiratory and critical care medicine\";s:9:\"\u0000*\u0000stitle\";s:29:\"Am. j. respir. crit. care med\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:3:\"177\";s:8:\"\u0000*\u0000issue\";s:1:\"2\";s:8:\"\u0000*\u0000spage\";s:3:\"195\";s:8:\"\u0000*\u0000epage\";s:3:\"201\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1073-449X\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"OBATA\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Hiroaki\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:14:\"SAKAI, Yoshiki\";i:1;s:17:\"OHNISHI, Shunsuke\";i:2;s:18:\"TAKESHITA, Satoshi\";i:3;s:12:\"MORI, Hidezo\";i:4;s:14:\"KODAMA, Makoto\";i:5;s:14:\"KANGAWA, Kenji\";i:6;s:17:\"AIZAWA, Yoshifusa\";i:7;s:17:\"NAGAYA, Noritoshi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:99:\"Single Injection of a Sustained-release Prostacyclin Analog Improves Pulmonary Hypertension in Rats\";s:8:\"\u0000*\u0000place\";s:12:\"New York, NY\";s:6:\"\u0000*\u0000pub\";s:25:\"American Lung Association\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"7\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:25:\"10.1164\/rccm.200703-349OC\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1164\/rccm.200703-349OC\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:99:\"Single Injection of a Sustained-release Prostacyclin Analog Improves Pulmonary Hypertension in Rats\";s:9:\"\u0000*\u0000jtitle\";s:58:\"American journal of respiratory and critical care medicine\";s:9:\"\u0000*\u0000stitle\";s:29:\"Am. j. respir. crit. care med\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:3:\"177\";s:8:\"\u0000*\u0000issue\";s:1:\"2\";s:8:\"\u0000*\u0000spage\";s:3:\"195\";s:8:\"\u0000*\u0000epage\";s:3:\"201\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1073-449X\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"OBATA\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Hiroaki\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:14:\"SAKAI, Yoshiki\";i:1;s:17:\"OHNISHI, Shunsuke\";i:2;s:18:\"TAKESHITA, Satoshi\";i:3;s:12:\"MORI, Hidezo\";i:4;s:14:\"KODAMA, Makoto\";i:5;s:14:\"KANGAWA, Kenji\";i:6;s:17:\"AIZAWA, Yoshifusa\";i:7;s:17:\"NAGAYA, Noritoshi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:99:\"Single Injection of a Sustained-release Prostacyclin Analog Improves Pulmonary Hypertension in Rats\";s:8:\"\u0000*\u0000place\";s:12:\"New York, NY\";s:6:\"\u0000*\u0000pub\";s:25:\"American Lung Association\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"7\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:11:\"BaseOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1164\/rccm.200703-349OC\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:99:\"Single Injection of a Sustained-release Prostacyclin Analog Improves Pulmonary Hypertension in Rats\";s:9:\"\u0000*\u0000jtitle\";s:58:\"American journal of respiratory and critical care medicine\";s:9:\"\u0000*\u0000stitle\";s:29:\"Am. j. respir. crit. care med\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:3:\"177\";s:8:\"\u0000*\u0000issue\";s:1:\"2\";s:8:\"\u0000*\u0000spage\";s:3:\"195\";s:8:\"\u0000*\u0000epage\";s:3:\"201\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1073-449X\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"OBATA\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Hiroaki\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:14:\"SAKAI, Yoshiki\";i:1;s:17:\"OHNISHI, Shunsuke\";i:2;s:18:\"TAKESHITA, Satoshi\";i:3;s:12:\"MORI, Hidezo\";i:4;s:14:\"KODAMA, Makoto\";i:5;s:14:\"KANGAWA, Kenji\";i:6;s:17:\"AIZAWA, Yoshifusa\";i:7;s:17:\"NAGAYA, Noritoshi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:99:\"Single Injection of a Sustained-release Prostacyclin Analog Improves Pulmonary Hypertension in Rats\";s:8:\"\u0000*\u0000place\";s:12:\"New York, NY\";s:6:\"\u0000*\u0000pub\";s:25:\"American Lung Association\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"7\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Base Search access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1164\/rccm.200703-349OC\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:99:\"Single Injection of a Sustained-release Prostacyclin Analog Improves Pulmonary Hypertension in Rats\";s:9:\"\u0000*\u0000jtitle\";s:58:\"American journal of respiratory and critical care medicine\";s:9:\"\u0000*\u0000stitle\";s:29:\"Am. j. respir. crit. care med\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:3:\"177\";s:8:\"\u0000*\u0000issue\";s:1:\"2\";s:8:\"\u0000*\u0000spage\";s:3:\"195\";s:8:\"\u0000*\u0000epage\";s:3:\"201\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1073-449X\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"OBATA\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Hiroaki\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:14:\"SAKAI, Yoshiki\";i:1;s:17:\"OHNISHI, Shunsuke\";i:2;s:18:\"TAKESHITA, Satoshi\";i:3;s:12:\"MORI, Hidezo\";i:4;s:14:\"KODAMA, Makoto\";i:5;s:14:\"KANGAWA, Kenji\";i:6;s:17:\"AIZAWA, Yoshifusa\";i:7;s:17:\"NAGAYA, Noritoshi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:99:\"Single Injection of a Sustained-release Prostacyclin Analog Improves Pulmonary Hypertension in Rats\";s:8:\"\u0000*\u0000place\";s:12:\"New York, NY\";s:6:\"\u0000*\u0000pub\";s:25:\"American Lung Association\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"7\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
