Two levels of protection for the B cell genome during somatic hypermutation
- Author
- MAN LIU1 ; DUKE, Jamie L2 ; RICHTER, Daniel J3 ; VINUESA, Carola G4 ; GOODNOW, Christopher C4 5 ; KLEINSTEIN, Steven H2 6 ; SCHATZ, David G1 7
[1] Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06510, United States
[2] Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut 06511, United States
[3] Broad Institute of MIT and Harvard,Cambridge Center, Cambridge, Massachusetts 02141, United States
[4] Division of Immunology and Genetics, John Curtin School of Medical Research, The Australian National University, Australia
[5] Australian Phenomics Facility, Canberra, ACT 2601, Australia
[6] Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06510, United States
[7] Howard Hughes Medical Institute, New Haven, Connecticut 06510, United States - Source
Nature (London). 2008, Vol 451, Num 7180, pp 841-845, 5 p ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- DNA Génome Lymphocyte B Mutation somatique Plaque Peyer Protection Réparation Activation-induced cytidine deaminase Hypermutation
- Keyword (en)
- DNA Genome B-Lymphocyte Somatic mutation Peyer patch Protection Repair
- Keyword (es)
- DNA Genoma Linfocito B Mutación somática Placa Peyer Protección Reparación
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C07 Mutagenesis. Repair
- Discipline
- Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20056750
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature06547 
https://dx.doi.org/10.1038/nature06547
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