Smooth Muscle Protein 22a-Mediated Patchy Deletion of Bmpr1a Impairs Cardiac Contractility but Protects Against Pulmonary Vascular Remodeling
- Author
- EL-BIZRI, Nesrine1 2 ; LINGLI WANG1 2 ; RABINOVITCH, Marlene1 2 ; MERKLINGER, Sandra L1 2 ; GUIGNABERT, Christophe1 2 ; DESAI, Tushar3 4 ; URASHIMA, Takashi1 2 ; SHEIKH, Ahmad Y5 ; KNUTSEN, Russell H6 ; MECHAM, Robert P6 ; MISHINA, Yuji7
[1] Department of Cardiopulmonary Research ProgramVera Moulton Wall Center for Pulmonary Vascular Disease, Stanford University School of Medicine, Calif, United States
[2] Department of Pediatrics, Stanford University School of Medicine, Calif, United States
[3] Department of Biochemistry, Stanford University School of Medicine, Calif, United States
[4] Department of Pulmonary and Critical Care Medicine, Stanford University School of Medicine, Calif, United States
[5] Department of Cardiothoracic Surgery, Stanford University School of Medicine, Calif, United States
[6] Department of Cell Biology Washington University School of Medicine, St Louis, Mo, United States
[7] Molecular Developmental Biology Group Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States - Source
Circulation research. 2008, Vol 102, Num 3, pp 380-388, 9 p ; ref : 43 ref
- CODEN
- CIRUAL
- ISSN
- 0009-7330
- Scientific domain
- Cardiology, blood circulation, phlebology
- Publisher
- Lippincott, Hagerstown, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Bmpr1a (Alk3) hypoxia pericyte pulmonary hypertension smooth muscle cell transgenic mice
- Keyword (fr)
- Animal transgénique Appareil circulatoire Contractilité Délétion Hypertension artérielle pulmonaire Hypoxie Mammalia Muscle lisse Poumon Protéine Péricyte Remodelage vasculaire Souris Appareil respiratoire Oxygène Pathologie de l'appareil circulatoire Pathologie de l'appareil respiratoire Rodentia Vertebrata
- Keyword (en)
- Transgenic animal Circulatory system Contractility Deletion Pulmonary hypertension Hypoxia Mammalia Smooth muscle Lung Protein Pericyte Vascular remodeling Mouse Respiratory system Oxygen Cardiovascular disease Respiratory disease Rodentia Vertebrata
- Keyword (es)
- Animal transgénico Aparato circulatorio Contractilidad Deleción Hipertensión arterial pulmonar Hipoxia Mammalia Músculo liso Pulmón Proteína Pericito Remodelado vascular Ratón Aparato respiratorio Oxígeno Aparato circulatorio patología Aparato respiratorio patología Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A22 Vertebrates: cardiovascular system
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11C Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases
- Discipline
- Pulmonology Vertebrates : cardiovascular system
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20085703
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1161/CIRCRESAHA.107.161059 
https://dx.doi.org/10.1161/CIRCRESAHA.107.161059
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